Platypnea-orthodeoxia syndrome is an uncommon condition of positional dyspnea and hypoxemia; symptoms occur when the patient is upright and resolve with recumbency. Causes can be broadly categorized into 4 groups: intracardiac shunting, pulmonary shunting, ventilation-perfusion mismatch, or a combination of these. Platypnea-orthodeoxia syndrome should be suspected when normal arterial oxygen saturations are recorded while an individual is supine, followed by abrupt declines in those saturations when upright. Further investigations with use of imaging and cardiac catheterization aid in the evaluation. When platypnea-orthodeoxia syndrome is due to intracardiac shunting without pulmonary hypertension, intracardiac shunt closure can be curative. In this article, we report a case of platypnea-orthodeoxia syndrome in an 83-year-old woman who was successfully treated by means of percutaneous transcatheter closure of an atrial septal defect.
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| http://dx.doi.org/10.14503/THIJ-14-4596 | DOI Listing |
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Article Synopsis
- Platypnea orthodeoxia syndrome (POS) is a rare cause of low oxygen levels that requires careful clinical evaluation and collaboration among specialists for diagnosis.
- An 86-year-old male presented to the ER with low oxygen saturation (84%) and did not improve with supplemental oxygen; however, his oxygen levels increased significantly when lying down.
- Diagnosis was confirmed through echocardiography revealing a large patent foramen ovale (PFO) causing a right-to-left shunt; he was treated successfully, improving his oxygen levels and allowing him to go home without supplemental oxygen.*
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