Design of multifunctional nanocarriers for delivery of anti-cancer therapy.

Curr Pharm Des

Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A & M Health Science Centre, Kingsville, Texas, USA 783 63.

Published: September 2016

Chemotherapy is the major and most widely used therapeutic strategy for the treatment of a wide variety of cancers. The non-specific/non-targeted drug delivery in chemotherapy leads to undesired side effects in normal and healthy tissues, and insufficient dosages to kill cancerous cells. Now-a-days, smart and intelligent multifunctional targeted nanomedicines based on various nanocarriers (dendrimers, carbon nanotubes, graphene, nanoparticles, quantum dots, self-emuslifying lipidic systems and carbon nanohorns etc) are being investigated promisingly in cancer treatment. In this article, we review the role of smart and intellegent multifucntional nanocarriers in delivery of chemotherapeutic agents with the aim to develop promising treatment strategy to combat with one of the killer of man kind i.e. cancer.

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Source
http://dx.doi.org/10.2174/1381612821666151027153106DOI Listing

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