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http://dx.doi.org/10.1186/2197-7364-1-S1-A73 | DOI Listing |
Sci Rep
December 2024
Rheonova, 1 Allee de Certéze, 38610, Gières, France.
Pulmonary mucus serves as a crucial protective barrier in the respiratory tract, defending against pathogens and contributing to effective clearance mechanisms. In Muco Obstructive Pulmonary Diseases (MOPD), abnormal rheological properties lead to highly viscous mucus, fostering chronic infections and exacerbations. While prior research has linked mucus viscoelasticity to its mucin content, the variability in MOPD patients implies the involvement of other factors.
View Article and Find Full Text PDFAnesthesiology
December 2024
Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA.
Background: Fentanyl is a synthetic opioid that is widely used in anesthesiology, but its illicit use is rapidly increasing. At high doses fentanyl induces unconsciousness and muscle rigidity, the mechanisms of which are poorly understood. Since animal models are needed to study these effects, the aim of this study was to establish a rat model of fentanyl abuse and investigate the effects of repeated high-dose fentanyl injections on loss of righting reflex, heart rate, respiratory depression, muscle, and brain activity.
View Article and Find Full Text PDFBMJ Case Rep
December 2024
Pediatrics, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India.
Foreign body (FB) aspiration in children is a common emergency. Traditionally, rigid bronchoscopy has been considered to be the mainstay for removal. However, in certain cases, flexible bronchoscopy can prove to be a better option and avoid thoracic surgery and unnecessary morbidity.
View Article and Find Full Text PDFCurr Opin Anaesthesiol
December 2024
Department of Anaesthesiology and Intensive Care Medicine, University Hospital, Otto-von-Guericke University.
Purpose Of The Review: The mediastinal mass syndrome (MMS) can occur after induction of anesthesia, intraoperatively or even days after the surgical procedure. The focus of this review is on the management of pediatric and adult patients with a significant mediastinal mass.
Recent Findings: The age distribution of patients with mediastinal lesions suggests a bimodal shape, with an increased incidence among children under 10 years old and adults aged 60-70 years old.
JTCVS Tech
December 2024
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Objective: To characterize the performance of titanium mesh (TM) (off-label) for rigid chest wall reconstruction at a single institution over a 5-year period.
Methods: Between January 1, 2019, and May 15, 2023, 22 patients (median age, 61 years) underwent chest wall resection with TM reconstruction at Cleveland Clinic. Indications for resection included sarcoma (n = 15), breast cancer (n = 2), lung cancer (n = 2), chondroblastoma (n = 1), and benign neoplasm (n = 2).
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