AI Article Synopsis
- The Paracoccidioides genus causes paracoccidioidomycosis (PCM), a serious fungal infection found mainly in Latin America.
- This study focuses on the differences in protein compositions between attenuated (weakened) and virulent (strong) isolates of Paracoccidioides brasiliensis, specifically the Pb18 strain.
- The research utilized stable isotopic dimethyl labeling for quantitative proteomic analysis, and the resulting data has been shared through the ProteomeXchange Consortium for further study.
Article Abstract
Paracoccidioides genus are the etiologic agents of paracoccidioidomycosis (PCM), a systemic mycosis endemic in Latin America. Few virulence factors have been identified in these fungi. This paper describes support data from the quantitative proteomics of Paracoccidioides brasiliensis attenuated and virulent isolates [1]. The protein compositions of two isolates of the Pb18 strain showing distinct infection profiles were quantitatively assessed by stable isotopic dimethyl labeling and proteomic analysis. The mass spectrometry and the analysis dataset have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with identifier PXD000804.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588363 | PMC |
| http://dx.doi.org/10.1016/j.dib.2015.09.001 | DOI Listing |
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