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Dietary Modification Patterns and Interventions Among Weight Loss Seekers in Tamil Nadu, South India: A Cross-Sectional Analysis of Intermittent Fasting and Alternative Dietary Approaches.
Cureus
December 2024
Community Medicine, Dhanalakshmi Srinivasan Medical College and Hospital, Siruvachur, IND.
Background The escalating global obesity epidemic requires comprehensive investigations for effective weight management strategies. Understanding the patterns, barriers, and facilitators of dietary interventions is crucial for developing effective weight management protocols. This research aims to assess dietary modification interventions among weight loss subjects in Tamilnadu, South India.
View Article and Find Full Text PDFPuberty Onset and Positive Urgency Explain Diminished Returns of Family Income on Tobacco and Marijuana Use.
Open J Psychol
January 2025
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Background: Puberty is a crucial developmental milestone that involves significant physiological, emotional, and behavioral changes. Early puberty onset, influenced by both biological and social factors, is associated with an increased risk of engaging in substance use, such as tobacco and marijuana. While high family income is generally linked to delayed puberty onset and lower behavioral risks, these benefits may not be equally protective for Black youth due to the phenomenon of Minorities' Diminished Returns (MDRs).
View Article and Find Full Text PDFBiologic Augmented Scaffold-based cartilage repair: Addressing Complications and Enhancing Outcomes.
J Clin Orthop Trauma
March 2025
Department of Orthopaedic Surgery, Sengkang General Hospital, Singapore.
Cartilage repair remains a significant challenge due to the tissue's limited innate regenerative capacity. Despite advances in techniques such as microfracture, autologous chondrocyte implantation (ACI), and osteochondral grafting, long-term outcomes are often compromised by complications, including suboptimal tissue integration, graft resorption, and mechanical instability. Recently, biologically augmented scaffold-based cartilage repair has emerged as a promising approach for full-thickness osteochondral lesions.
View Article and Find Full Text PDFAlcohol Use Disorder and Alcohol-Associated Liver Disease: New Definitions, Screening, and Treatment.
Gastroenterol Hepatol (N Y)
November 2024
Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York.
Alcohol-associated liver disease (ALD) poses a significant global health burden and is a leading cause of liver-related morbidity and mortality. ALD encompasses a spectrum of disease states ranging from asymptomatic steatosis to acute hepatitis and cirrhosis. Alcohol use disorder (AUD) significantly increases the risk of developing ALD, and insight into AUD can provide a more complete understanding of ALD and the patients affected by these interrelated diseases.
View Article and Find Full Text PDFFrom prediction to practice: mitigating bias and data shift in machine-learning models for chemotherapy-induced organ dysfunction across unseen cancers.
BMJ Oncol
November 2024
Department of Computer Science, Durham University, Durham, UK.
Objectives: Routine monitoring of renal and hepatic function during chemotherapy ensures that treatment-related organ damage has not occurred and clearance of subsequent treatment is not hindered; however, frequency and timing are not optimal. Model bias and data heterogeneity concerns have hampered the ability of machine learning (ML) to be deployed into clinical practice. This study aims to develop models that could support individualised decisions on the timing of renal and hepatic monitoring while exploring the effect of data shift on model performance.
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