Introduction: Metabolic syndrome (MS) is a condition described by the group of risk factors associated with obesity that raise the risk of cardiovascular disease and type 2 diabetes. MS has an increasing trend in developing countries with change of diet and lifestyle. Many studies in India have reported high prevalence of MS among general population however there is little information available about the same in working population.
Material And Methods: The present study was conducted among 281 mine employees from an organized mining company from Southern India. The workers were classified into different sub occupational groups according to ISCO-88. WHO Criteria was used for the diagnosis of MS.
Results: The overall prevalence of MS in mine employees was about 17%. Among different sub occupations, the highest was observed in professional group of 52.9% and lowest in elementary occupations of 9.4%. In other sub occupational groups it was 23.3% in clerical, 18.9% in trade workers, 17.5% in technicians and 15.5% in machine operators. Occurrence of MS when compared in different sub occupations was statistically significant (P = <0.001). Further MS was found to be 6.4% in the 18-30 years of age group which significantly increased to 40.3% in the 51-60 years age group suggesting direct relation of MS with increase in age.
Discussion: Mining being physical demanding occupation prevalence of MS is assumed to be lower than the general population; however it was observed that the prevalence is in similar line to that of general population with the prevalence ranging from 9.4% to 52.9% among different sub occupations. Hence it is concluded that there is need of health education and promotion among the mine workers.
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http://dx.doi.org/10.4103/0019-5278.165330 | DOI Listing |
Diabetes
January 2025
Department of Biology & Institute of Biochemistry, Carleton University, Ottawa, ON, Canada.
Cancer survivors have an increased risk of developing Type 2 diabetes compared to the general population. Patients treated with cisplatin, a common chemotherapeutic agent, are more likely to develop metabolic syndrome and Type 2 diabetes than age- and sex-matched controls. Surprisingly, the impact of cisplatin on pancreatic islets has not been reported.
View Article and Find Full Text PDFPediatr Nephrol
January 2025
Nephrology, Children's National Hospital, 111 Michigan Avenue NW, Washington, DC, 20010, USA.
Background: Obesity and metabolic syndrome (MS) accelerate arterial stiffening, increasing cardiovascular (CV) risk after transplant. BMI is limited by inability to differentiate muscle, fat mass, and fat distribution patterns. The aim of this study was to identify the best anthropometric measure to detect arterial stiffness as assessed by pulse wave velocity (PWV) in a racially diverse pediatric transplant population.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Cardiovascular Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
The present investigation evaluated the potential impacts of morin, a natural flavonoid, against cardiovascular disorders. Since inception until September 2024, PubMed, Scopus, and Web of Science have been searched extensively. The process involved eliminating duplicate entries and conducting a systematic review of the remaining studies post-full-text screening.
View Article and Find Full Text PDFJ Comp Eff Res
January 2025
Guy's & St Thomas' NHS Foundation Trust, London, UK.
Alagille syndrome (ALGS) is a rare, cholestatic multiorgan disease associated with bile duct paucity, leading to cholestasis. Clinical symptoms of cholestasis include debilitating pruritus, xanthomas, fat-soluble vitamin deficiencies, growth failure, renal disease and impaired health-related quality of life (HRQoL). The main objective was to review the current literature on the epidemiological, clinical, psychosocial and economic burden of ALGS in view of the development of ileal bile acid transporter (IBAT) inhibitors.
View Article and Find Full Text PDFTurk J Pediatr
December 2024
Department of Pediatric Cardiology, Ankara Bilkent City Hospital, Ankara, Türkiye.
Background: We aimed to evaluate how the parameters used in the diagnosis of metabolic syndrome (MetS) and parameters such as epicardial adipose tissue (EAT) thickness, insulin resistance (IR), and serum uric acid (SUA) are affected according to the severity of obesity.
Methods: A total of 120 obese patients aged 10-18 years were classified as class 1-2-3 according to their body mass index (BMI) score. SUA was measured and oral glucose tolerance tests were performed on all patients.
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