Purpose: To assess the effectivity of photodynamic therapy (PDT) for the treatment of retinal capillary haemangiomas
Method: Retrospective case note analysis of all patients with retinal angiomas treated with PDT between 2003 and 2010.
Results: Six eyes of 6 patients (3 male, 3 female) with a mean age of 50 years (range, 23-78) were identified in our database. The follow up period was between 24 and 60 months (mean, 36). Tumor regression was evident in two patients; three tumors showed no demonstrable response to treatment on ophthalmoscopy or ultrasonography and one tumor progressed despite PDT and subsequent cryotherapy. One patient developed retinal neovascularisations following a period of inattendence to our clinic. Visual acuity improved in two patients following PDT, deteriorated in three patients and remained stable in a one patient.
Conclusion: The response of retinal haemangioblastomas to PDT is inconsistent. Other treatment modalities ought to be utilized for peripheral lesions, however PDT may be tried in juxtapapillary lesions where radiotherapy or cryotherapy is likely to result in concurrent visual loss.
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| http://dx.doi.org/10.1016/j.pdpdt.2015.10.008 | DOI Listing |
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