AI Article Synopsis
- Early diagnosis of ectopic pregnancy (EP) is crucial to prevent life-threatening complications in the first trimester.
- A study compared adenosine deaminase (ADA) levels in 41 patients with unruptured EP to 42 pregnant women with normal fetal development, finding higher ADA levels in the EP group.
- The optimal ADA threshold for predicting EP was identified as 10.95 IU/L, with 56% sensitivity and 67% specificity, indicating that high ADA levels could aid in early diagnosis, but further research is needed.
Article Abstract
Early diagnosis of ectopic pregnancy (EP) is important due to life-threatening consequences in the first trimester of pregnancy. In this study we aimed to investigate the role of adenosine deaminase (ADA) activity in the prediction of EP. Forty-one patients with unruptured ectopic pregnancy comprised the case group and forty-two first trimester pregnant women with shown foetal heart beating in ultrasound comprised the control group. The mean ADA level in EP (10.9 ± 3.0 IU/L) was higher than that in control group (9.2 ± 3.6 IU/L) (p = 0.018). Receiver operating characteristics or ROC curve identified ADA value of 10.95 IU/L as optimal threshold for the prediction of EP with 56% sensitivity and 67% specificity. High ADA levels are valuable in the early diagnosis of EP. However more comprehensive studies are required.
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| http://dx.doi.org/10.3109/01443615.2015.1065228 | DOI Listing |
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