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Blastic plasmacytoid dendritic cell neoplasm: a Swiss case series of a very rare disease and a structured review of the literature.
Swiss Med Wkly
January 2025
Department of Internal Medicine, Clinic for Medical Oncology and Hematology, Municipal Hospital Zurich Triemli, Zurich, Switzerland.
Introduction: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a very rare disease, with unique diagnostic challenges and often dismal outcome. There are no widely accepted treatment guidelines available. Lymphoma-like regimens with or without autologous or allogenic transplantation were the cornerstone of most therapeutic concepts.
View Article and Find Full Text PDFThe graded heat-health risk forecast and early warning with full-season coverage across China: a predicting model development and evaluation study.
Lancet Reg Health West Pac
January 2025
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing, China.
Background: Due to global climate change, high temperature and heatwaves have become critical issues that pose a threat to human health. An effective early warning system is essential to mitigate the health risks associated with high temperature and heatwaves. However, most of the current heatwave early warning systems are not adequately developed based on the heat-health risk model, and the health impact of hot weather has not been well managed in most countries.
View Article and Find Full Text PDFThe Characteristics of the Metabolomic Profile in Patients with Parkinson's Disease and Vascular Parkinsonism.
Acta Naturae
January 2024
Novosibirsk State University, Novosibirsk, 630090 Russian Federation.
The gradually increasing age of the world population implies that the prevalence of neurodegenerative diseases also continues to rise. These diseases are characterized by a progressive loss of cognitive and motor functions. Parkinson's disease, which involves the gradual death of specialized neural tissue, is a striking example of a neurodegenerative process.
View Article and Find Full Text PDFAnxiety mediates the relationship between caregiver burden and preparedness in individuals with acquired brain injury: meta-analytic structural equation modeling.
Brain Inj
January 2025
Department of Nursing, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Background: Informal caregivers of individuals with acquired brain injury (ABI) often lack adequate preparedness for caregiving. Caregiver burden may reduce preparedness, with anxiety potentially mediating this relationship. However, these associations remain unclear.
View Article and Find Full Text PDFBrain Age as a New Measure of Disease Stratification in Huntington's Disease.
Mov Disord
January 2025
School of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Melbourne, Victoria, Australia.
Background: Despite advancements in understanding Huntington's disease (HD) over the past two decades, absence of disease-modifying treatments remains a challenge. Accurately characterizing progression states is crucial for developing effective therapeutic interventions. Various factors contribute to this challenge, including the need for precise methods that can account for the complex nature of HD progression.
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