Adrenal Pheochromocytoma Incidentally Discovered in a Patient With Parkinsonism.

Medicine (Baltimore)

From the Specialized Center of Secondary Hypertension (LP, AC, CM, LZ, CL); Department of Internal Medicine and Medical Specialties (LP, AC, CM, LZ, GI, PL, CL); and Department of Radiology, Section Nuclear Medicine, University of Rome "La Sapienza," Rome, Italy (GDV).

Published: October 2015

To evaluate the diagnostic route of pheochromocytoma (PHEO) in a patient under dopaminergic treatment.A 70-year-old man with Parkinsonism and under treatment with levodopa and carbidopa came to our observation for evaluation of arterial hypertension and right adrenal mass discovered incidentally.To evaluate adrenal hormone levels we performed a dexamethasone suppression test, plasma aldosterone levels and 24-hr urinary metanephrine, which revealed elevated levels of catecholamines metabolities. 123-I-metaiodobenzylguanidine SPECT scintiscan revealed raised activity within the right adrenal gland concordant with the mass. The diagnosis of PHEO was posed and an elective laparoscopic adrenalectomy was performed; histopathological examination confirmed the PHEO diagnosis.Recently the coexistence of PHEO and Parkinsonism is a very rare association of diseases, with only 3 cases reported in literature. In this article, another case is reported and diagnostic procedures are discussed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620812PMC
http://dx.doi.org/10.1097/MD.0000000000001855DOI Listing

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