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Early functional and structural hippocampal impairment in a bilateral common carotid artery stenosis mouse model.
Animal Model Exp Med
January 2025
Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.
Background: Subcortical ischemic vascular dementia (SIVD) is a common subtype of vascular dementia. Currently, the bilateral common carotid artery stenosis (BCAS) mouse model is the most suitable SIVD rodent model. In this study, we investigated the functional and structural impairments in the hippocampus 1 month after BCAS.
View Article and Find Full Text PDFSurgical Management of Intestinal Obstruction Secondary to Barium Impaction: Two Exemplary Cases.
Cureus
December 2024
Surgery, New York University (NYU) Langone Health/New York University (NYU) Winthrop Hospital, Mineola, USA.
A "barium chemobezoar" or "barolith" is a rare but serious cause of intestinal obstruction. We present two cases, a 70-year-old female patient and a 61-year-old male patient, both requiring urgent surgery for barolith-induced bowel obstruction. Diagnostic challenges were encountered in both cases, with imaging raising suspicion for barolith formation after prior barium use.
View Article and Find Full Text PDFSevelamer-induced Gastrointestinal Mucosal Injury: A Critical Review for Clinicians.
J Community Hosp Intern Med Perspect
November 2024
Gastroenterology & Hepatology, St. Joseph's University Medical Center, Paterson, USA.
Sevelamer is a non-absorbable polymer used to treat hyperphosphatemia in individuals with end-stage renal disease (ESRD) undergoing hemodialysis. The deposition of sevelamer crystals in the gastrointestinal (GI) tract, especially in the colon, can cause mucosal inflammation, pseudopolyps, ulceration, ischemia, or necrosis. Owing to its rarity and lack of physician awareness, the actual incidence and prevalence of sevelamer-induced gastrointestinal mucosal injury (SIGMI) remain unknown.
View Article and Find Full Text PDFSmall intestinal obstruction caused by the gastric bezoars in elderly diabetic patients: A case report.
Int J Surg Case Rep
December 2024
School of Clinical Medical College, Hebei University, Baoding 071000, China; Department of Digestive Medicine, Affiliated Hospital of Hebei University, Baoding 071000, China.
Introduction: Bezoar is an unusual cause of small bowel obstruction accounting for 0.4-4 % of all mechanical bowel obstruction. With the rising incidence of diabetes and the associated risk of gastrointestinal issues.
View Article and Find Full Text PDFIncidence and Factors in Delayed Neurological Deficits after Subarachnoid Hemorrhage in Mice.
Brain Hemorrhages
June 2024
The Vivian L. Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Background: Delayed cerebral ischemia (DCI) is one of the most feared complications in aneurysmal subarachnoid hemorrhage (SAH). Animal models are crucial to studying the disease mechanisms and potential treatments. DCI in rodents was thought to not exist; herein we examine literature and our experience with DCI in rodents.
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