An unexpected acid-mediated cascade reaction induced by conjugate addition of sulfinamides to dienediones has been developed. This highly efficient Rauhut-Currier reaction enables the rapid, high-yielding construction of sulfonated cyclopentanes with three contiguous stereogenic centers in a single operation starting from simple sulfinamides. This process constitutes the first example of sulfinamide-promoted cycloisomerization.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/chem.201502816 | DOI Listing |
Publication Analysis
Top Keywords
sulfonated cyclopentanes
8
rauhut-currier reaction
8
access highly
4
highly functionalized
4
functionalized sulfonated
4
cyclopentanes acid-promoted
4
acid-promoted rauhut-currier
4
reaction sulfinamides
4
sulfinamides unexpected
4
unexpected acid-mediated
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!