A Rare Cause of Reversible Renal Hemosiderosis.

Case Rep Nephrol

Division of Nephrology, The Ottawa Hospital and University of Ottawa, Ottawa, ON, Canada K1H 7W9.

Published: October 2015

Kidney failure secondary to renal hemosiderosis has been reported in diseases with intravascular hemolysis, like paroxysmal nocturnal hemoglobinuria, and valvular heart diseases. We present here a case of hemosiderin induced acute tubular necrosis secondary to intravascular hemolysis from Clostridium difficile infection with possible role of supratherapeutic INR. We discuss the pathophysiology, causes, and prognosis of acute tubular injury from hemosiderosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605264PMC
http://dx.doi.org/10.1155/2015/464059DOI Listing

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