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Feed additives for methane mitigation: Recommendations for identification and selection of bioactive compounds to develop antimethanogenic feed additives.
J Dairy Sci
January 2025
Estación Experimental del Zaidín, CSIC, 18008 Granada, Spain. Electronic address:
Despite the increasing interest in developing antimethanogenic additives to reduce enteric methane (CH) emissions and the extensive research conducted over the last decades, the global livestock industry has a very limited number of antimethanogenic feed additives (AMFA) available that can deliver substantial reduction, and they have generally not reached the market yet. This work provides technical recommendations and guidelines for conducting tests intended to screen the potential to reduce, directly or indirectly, enteric CH of compounds before they can be further assessed in in vivo conditions. The steps involved in this work cover the discovery, isolation, and identification of compounds capable of affecting CH production by rumen microbes, followed by in vitro laboratory testing of potential candidates.
View Article and Find Full Text PDFdrMD: Molecular Dynamics for Experimentalists.
J Mol Biol
December 2024
School of Biological Sciences, University of Edinburgh, Roger Land Building, Edinburgh EH9 3FF.
Molecular dynamics (MD) simulations can be used by protein scientists to investigate a wide array of biologically relevant properties such as the effects of mutations on a protein's structure and activity, or probing intermolecular interactions with small molecule substrates or other macromolecules. Within the world of computational structural biology, several programs have become popular for running these simulations, but each of these programs requires a significant time investment from the researcher to run even simple simulations. Even after learning how to run and analyse simulations, many elements remain a "black box.
View Article and Find Full Text PDFDeciphering the mineral code of urinary stones: A first look at zinc isotopes.
Environ Pollut
December 2024
Nu instruments, Wrexham Industrial Estate, 74 Clywedog Road South, Wrexham LL13 9XS, United Kingdom.
Zinc (Zn) is an essential element for all living organisms, and Zn isotopes play a key role in studying the formation of disease. Despite extensive studies on Zn isotopes in healthy and diseased human tissues, the role of Zn isotopes in urinary stones remains unexplored. This study investigates Zn isotopes in 37 urinary stones using multi-collector inductively coupled plasma mass spectrometry.
View Article and Find Full Text PDFNanocellulose synthesis via synergistic application of solid acid and cellulase.
Int J Biol Macromol
December 2024
Key Laboratory of Agricultural Product Processing and Quality Control of Specialty(Co-construction by Ministry and Province), School of Food Science and Technology, Shihezi University, Shihezi, Xinjiang 832003, China; Key Laboratory for Food Nutrition and Safety Control of Xinjiang Production and Construction Corps, School of Food Science and Technology, Shihezi University, Shihezi, Xinjiang 832003, China. Electronic address:
Nanocellulose stands out in numerous applications due to its excellent properties. Yet, achieving its preparation in a cost-effective, efficient, and environmentally benign manner remains challenging. This study introduces a green synthesis approach by employing a non-polluting solid acid, combined with a cellulase enzyme, for nanocellulose production.
View Article and Find Full Text PDFAdaptive capacity and attainment of the sustainable development goals in local communities of India.
J Environ Manage
December 2024
Institute of Rural Management Anand, Gujarat, India. Electronic address:
India's progress vis-à-vis the United Nations' Sustainable Development Goals (SDG) has stagnated since 2020. The consequences of the non-attainment of the SDGs can be severe. Therefore, questions arise as to what steps must be taken to accelerate progress in India's SDG attainment.
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