Gene expression analysis of laryngeal squamous cell carcinoma.

Genom Data

Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, SP CEP 14049-900, Brazil ; National Institute of Science and Technology in Stem Cell and Cell Therapy and Center For Cell-Based Therapy, Rua Tenente Catão Roxo, 2501, Monte Alegre, Ribeirão Preto, SP CEP 14051-140, Brazil ; Center for Integrative Systems Biology, CISBi, NAP/USP, Rua Catão Roxo, 2501, Monte Alegre, Ribeirão Preto, SP CEP 14051-140, Brazil.

Published: September 2015

AI Article Synopsis

  • Laryngeal squamous cell carcinoma (LSCC) is a prevalent type of head and neck cancer often linked to lifestyle choices like smoking and drinking.
  • A study was conducted involving gene expression profiling of 31 patients diagnosed with LSCC to identify potential new targets that might be involved in the development of this cancer.
  • The research aims to enhance the understanding of LSCC biology and potentially lead to better treatment strategies.

Article Abstract

Laryngeal squamous cell carcinoma (LSCC) is one of the most common malignancies of the head and neck tumors Zhang et al., 2013 [1]). Previous studies have associated its occurrence with social activities, such as tobacco and alcohol consumption (Hashibe et al., 2007a [2]; Hashibe et al., 2007b [3]; Shangina et al., 2006 [4]). Here, we performed a genome-wide gene expression profiling in thirty-one patients positively diagnosed for LSCC, in order to investigate new targets involved in tumorigenesis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583618PMC
http://dx.doi.org/10.1016/j.gdata.2015.04.024DOI Listing

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