Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10858-015-9996-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Retinoid X receptor agonist 9CDHRA mitigates retinal ganglion cell apoptosis and neuroinflammation in a mouse model of glaucoma.
FASEB J
March 2025
Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.
Glaucoma, a leading cause of irreversible blindness, is characterized by the progressive loss of retinal ganglion cells (RGCs) and optic nerve damage, often associated with elevated intraocular pressure (IOP). Retinoid X receptors (RXRs) are ligand-activated transcription factors crucial for neuroprotection, as they regulate gene expression to promote neuronal survival via several biochemical networks and reduce neuroinflammation. This study investigated the therapeutic potential of 9-cis-13,14-dihydroretinoic acid (9CDHRA), an endogenous retinoid RXR agonist, in mitigating RGC degeneration in a high-IOP-induced experimental model of glaucoma.
View Article and Find Full Text PDFAssessing Environmental Justice in Mexico: How Polluting Industries and Healthcare Disparities Impact Congenital Heart Defects.
Birth Defects Res
March 2025
Neurometabolic Translational Research Center for Experimental Neurotherapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Background: Congenital heart defects (CHDs) are the most prevalent birth defects globally and the second leading cause of death in Mexican children under five. This study examines how industrial activity and social vulnerabilities independently and jointly influence CHD incidence across 2446 Mexican municipalities from 2008 to 2019.
Methods: Using negative binomial regression models, we evaluated associations between polluting industries, healthcare access, and CHD incidence.
Investigation of structural and dynamic properties of the Butyrophilin BTN3A1/BTN2A1 cytoplasmic complex by F solution NMR.
FASEB J
March 2025
Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.
Butyrophilin 3A1 (BTN3A1) is an integral membrane protein capable of detecting phosphoantigens, like (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate (HMBPP), through its internal B30.2 domain. Detection of phosphoantigens leads to interactions with butyrophilin 2A1 and the subsequent activation of γδ-T cells.
View Article and Find Full Text PDFHeteroatom Introduction and Electrochemical Reconstruction on Heterostructured Co-Based Electrocatalysts for Hydrogenation of Quinolines.
Small
March 2025
Department of Applied Chemistry, Petroleum and Chemical Industry Key Laboratory of Organic Electrochemical Synthesis, State Key Laboratory of Green Chemistry Synthesis Technology, Zhejiang University of Technology, Hangzhou, 310014, P. R. China.
Electrocatalytic hydrogenation (ECH) of quinoline provides an eco-friendly and prospective route to achieve the highly value-added generation of 1,2,3,4-tetrahydroquinoline (THQ). Co element has been proven to be the efficient catalytic site for ECH of quinoline, but the rational regulation of the electronic structure of active Co site to improve the activity is still a challenge. Herein, the hierarchical core-shell structure consisting of NiCo-MOF nanosheets encapsulated Cu(OH) nanorods (Cu(OH)@CoNi-MOF) is constructed.
View Article and Find Full Text PDFNanofibrous Hydrogel with Highly Salt-Resistant Radial/Vertical-Combined Structure for Efficient Solar Interfacial Evaporation.
Small
March 2025
College of Textile and Clothing Engineering, National Engineering Laboratory for Modern Silk, Soochow University, Suzhou, 215021, P. R. China.
Hydrogel-based solar interfacial evaporators, featuring various channels such as random, unidirectional, and radial array, are considered effective for seawater desalination owing to their porous structure, lower evaporation enthalpy, and controllable water transport capacity. However, each individual array structure has its own strengths and limitations, influencing water transportation, thermal management, and salt rejection. By combining the benefits of each array configuration into a single evaporator, the evaporation performance can be maximized.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!