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Secondary Hemophagocytic Lymphohistiocytosis in a Patient With Favorable Histology Wilms Tumor. | LitMetric

Secondary Hemophagocytic Lymphohistiocytosis in a Patient With Favorable Histology Wilms Tumor.

J Pediatr Hematol Oncol

Departments of *Pediatrics †Pathology, University of California San Diego, San Diego, CA.

Published: November 2015

Secondary hemophagocytic lymphohistiocytosis (HLH) is most commonly associated with malignancy, infection, or an underlying autoimmune disorder. Malignancy-associated hemophagocytic syndrome is responsible for most secondary HLH cases, but it has not been well described in children. We present a case of a 4-year-old female with favorable histology of Wilms tumor who developed secondary HLH after unsuccessful resection of the tumor and initiation of chemotherapy.

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Source
http://dx.doi.org/10.1097/MPH.0000000000000433DOI Listing

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