Why so many sperm cells?

Commun Integr Biol

Group of Computational Biology and Applied Mathematics ; IBENS, CNRS-INSERM U1024, Ecole Normale Supérieure ; Paris, France.

Published: October 2015

AI Article Synopsis

  • The search for an oocyte by spermatozoa represents a major challenge in fertility, where out of millions, only one sperm successfully reaches the oocyte.
  • This intense selection process is thought to be shaped by evolution, but its purpose and implications are not yet fully understood.
  • The article calls for new interdisciplinary research to explore these questions and improve our understanding of fertility mechanisms.

Article Abstract

A key limiting step in fertility is the search for the oocyte by spermatozoa. Initially, there are tens of millions of sperm cells, but a single one will make it to the oocyte. This may be one of the most severe selection processes designed by evolution, whose role is yet to be understood. Why such a huge redundancy is required and what does that mean for the search process? we discuss here these questions and consequently new lines of interdisciplinary research needed to find possible answers.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594528PMC
http://dx.doi.org/10.1080/19420889.2015.1017156DOI Listing

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