AI Article Synopsis

  • Pseudoangiomatous stromal hyperplasia (PASH) is a benign condition of the breast characterized by mesenchymal growth, first identified by Vuitch et al.
  • A 46-year-old woman experienced significant, painful swelling in both breasts over six weeks, without any prior injury, leading to further investigation.
  • The case highlights the importance of recognizing PASH as a possible cause of rapid and painful breast enlargement, especially as it is often found incidentally during biopsies for other breast issues.

Article Abstract

Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a benign mesenchymal proliferative process, initially described by Vuitch et al. We report an unusual case of a 46-year-old woman who presented with a 6-week history of bilateral massive, asymmetrical, painful enlargement of her breasts, without a history of trauma. On clinical examination, both breasts were markedly enlarged and oedematous, but there were no discrete palpable masses. Preoperative image-guided core biopsies and surgery showed PASH. PASH is increasingly recognised as an incidental finding on image-guided core biopsy performed for screen detected lesions. There are a few reported cases of PASH presenting as rapid breast enlargement. In our case, the patient presented with painful, asymmetrical, massive breast enlargement. Awareness needs to be raised of this entity as a differential diagnosis in massive, painful breast enlargement.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612527PMC
http://dx.doi.org/10.1136/bcr-2014-204343DOI Listing

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