Hybrid cells were produced from Echinococcus multilocularis metacestode germinal cells and murine tumor cells. Small colonies were formed which, while ceasing to grow after a few generations, remained viable for at least 10 weeks. These hybridoma cells secrete antigen(s) reacting in indirect immunofluorescence and ELISA specifically with sera from patients suffering from an E. multilocularis infection. The antigen(s) appear suitable for the differential diagnosis of E. multilocularis and E. granulosus. Thus, hybridoma cells may produce helminth antigens.

Download full-text PDF

Source
http://dx.doi.org/10.1016/0014-4894(89)90096-9DOI Listing

Publication Analysis

Top Keywords

echinococcus multilocularis
8
metacestode germinal
8
germinal cells
8
cells murine
8
murine tumor
8
tumor cells
8
hybridoma cells
8
cells
7
multilocularis vitro
4
vitro secretion
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!