Microalgae are a source of numerous compounds that can be used in many branches of industry. Synthesis of such compounds in microalgal cells can be amplified under stress conditions. Exposure to various metals can be one of methods applied to induce cell stress and synthesis of target products in microalgae cultures. In this review, the potential of producing diverse biocompounds (pigments, lipids, exopolymers, peptides, phytohormones, arsenoorganics, nanoparticles) from microalgae cultures upon exposure to various metals, is evaluated. Additionally, different methods to alter microalgae response towards metals and metal stress are described. Finally, possibilities to sustain high growth rates and productivity of microalgal cultures in the presence of metals are discussed.
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http://dx.doi.org/10.3390/ijms161023929 | DOI Listing |
Mar Drugs
December 2024
Interdepartmental Centre of Environmental Science and Engineering (CINSA), University of Cagliari, Via San Giorgio 12, 09124 Cagliari, Italy.
The green synthesis of silver (Ag) and zinc oxide (ZnO) nanoparticles (NPs), as well as Ag/AgO/ZnO nanocomposites (NCs), using polar and apolar extracts of , offers a sustainable method for producing nanomaterials with tunable properties. The impact of the synthesis environment and the nanomaterials' characteristics on cytotoxicity was evaluated by examining reactive species production and their effects on mitochondrial bioenergetic functions. Cytotoxicity assays on PC12 cells, a cell line originated from a rat pheochromocytoma, an adrenal medulla tumor, demonstrated that Ag/AgO NPs synthesized with apolar (Ag/AgO NPs A) and polar (Ag/AgO NPs P) extracts exhibited significant cytotoxic effects, primarily driven by Ag ion release and the disruption of mitochondrial function.
View Article and Find Full Text PDFActa Biomater
December 2024
Department of Ultrasound, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu, PR China. Electronic address:
Dynamic therapies such as photodynamic therapy (PDT) and sonodynamic therapy (SDT) have potential in cancer treatment. Microalgae have attracted increasing attention because of their high active mobility, flexibility in terms of functionality, and good biocompatibility. In this study, surface-engineered microalgae Chlorella vulgaris (Chl) modified with metal‒organic framework (MOF) nanoparticles (denoted Chl-MOF) are successfully developed for synergistic photo-sonodynamic therapy and immunotherapy.
View Article and Find Full Text PDFAquat Toxicol
December 2024
Key Laboratory of Marine Chemistry Theory and Technology of the Ministry of Education, Ocean University of China, Qingdao 266100, China. Electronic address:
A large number of nanoparticles are produced and enter the aquatic environment, where they interact with each other, posing a potential threat to aquatic organisms. The toxicity of two types of nanoparticles (nCu and nSiO) on Nitzschia closterium f. minutissima (N.
View Article and Find Full Text PDFNanotechnology
December 2024
School of Advanced Materials and Nanotechnology, Xidian University, Xi'an 710126, People's Republic of China.
Semiconducting and metallic nanomaterials are essential building blocks for developing modern-age technologies, and their demand is expanding exponentially with a growing population. However, their processing impacts the ecosystem and requires urgently sustainable solutions. This perspective underlines the emergence of microbe-mediated (bacteria, yeast, fungi, microalgae, viruses, cyanobacteria) green nanomaterials, including metal-based, carbon-based, organic and hybrid nanomaterials, with technical challenges of scalability, stability and cytotoxicity restricting their transition from lab-to-market.
View Article and Find Full Text PDF3 Biotech
December 2024
Amity Institute of Nanotechnology, Amity University, Noida, Uttar Pradesh 201313 India.
Unlabelled: In the present study, CeO nanoparticles were synthesized using one-pot green route with high yield using microalgae The synthesized CeO nanoparticles (CeO-np) exhibited rapid photocatalytic degradation 98.2% of doxycycline (DC) (20 mg/L) in only 30 min under visible light at pH7 in water. It was encouraging that CeO-np did not demonstrate a loss of photocatalytic activity up to five repeated cycles, confirming its stability during the degradation process.
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