Background: Over the last decade surgical treatments for migraine involving proposed trigger sites have been described and popularized by plastic surgeons in particular. Various related techniques aim to free up "trigger sites" by removal of small facial muscles or "decompressing" small facial nerves.
Discussion: The basis for migraine trigger site surgery is without merit. There is one positive placebo controlled study with many limitations. Natural history and placebo mechanisms explain the outcomes from migraine surgery. The American Headache Society recommends that the migraine surgery not be performed outside of a clinical trial.
Conclusion: Migraine trigger site surgery should not be performed.
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http://dx.doi.org/10.1111/head.12715 | DOI Listing |
Brain Sci
January 2025
Department of Neurology, National Hospital for Neurology and Neurosurgery, London WC1N 3BG, UK.
Acute vertigo or dizziness is a frequent presentation to the emergency department (ED), making up between 2.1% and 4.4% of all consultations.
View Article and Find Full Text PDFJ Neurosci Methods
January 2025
Department of Neurosurgery, Carl-von-Ossietzky University Oldenburg, Oldenburg, Germany; Research Center Neurosensory Science, Carl-von-Ossietzky University Oldenburg, Germany. Electronic address:
Background: Spreading depolarization (SD) is an electrophysiological phenomenon of massive neuronal depolarization that occurs in a multitude of brain injuries. Clinical studies and experimental data have linked the occurrence of SDs with secondary brain damage. However, there is a translational gap because of methodological limitations between clinical and experimental approaches focusing on short-term effects.
View Article and Find Full Text PDFBrain
January 2025
Institute of Neurological Sciences and Psychiatry, Hacettepe University, 06100, Ankara, Turkey.
Cortical spreading depolarization (CSD), the neurophysiological event believed to underlie aura, may trigger migraine headaches through inflammatory signaling that originates in neurons and spreads to the meninges via astrocytes. Increasing evidence from studies on rodents and migraine patients supports this hypothesis. The transition from pro-inflammatory to anti-inflammatory mechanisms is crucial for resolving inflammation.
View Article and Find Full Text PDFCephalalgia
January 2025
Department of Pharmacology, University of Arizona College of Medicine, Tucson, AZ, USA.
Background: Women with endometriosis are more likely to have migraine. The mechanisms underlying this co-morbidity are unknown. Prolactin, a neurohormone secreted and released into circulation from the anterior pituitary, can sensitize sensory neurons from female, but not male, rodents, monkeys and human donors.
View Article and Find Full Text PDFCureus
December 2024
College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, SAU.
Introduction: Migraines pose a significant risk to the health of individuals who suffer from them. Consequently, healthcare specialists must have sufficient knowledge and awareness to recognize and treat migraines. This study aimed to assess medical students' knowledge and perception of migraine-triggering factors and management methods.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!