MERS, SARS, and Ebola: The Role of Super-Spreaders in Infectious Disease.

Cell Host Microbe

CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China; Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112, China; Office of Director-General, Chinese Center for Disease Control and Prevention, Beijing 102206, China. Electronic address:

Published: October 2015

Super-spreading occurs when a single patient infects a disproportionate number of contacts. The 2015 MERS-CoV, 2003 SARS-CoV, and to a lesser extent 2014-15 Ebola virus outbreaks were driven by super-spreaders. We summarize documented super-spreading in these outbreaks, explore contributing factors, and suggest studies to better understand super-spreading.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128246PMC
http://dx.doi.org/10.1016/j.chom.2015.09.013DOI Listing

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