Tumor Microenvironment as a New Target for Tumor Immunotherapy of Polysaccharides.

Crit Rev Food Sci Nutr

a State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang , Jiangxi , China.

Published: July 2016

Many researches show that polysaccharides derived from fungi and plants have strong pharmacological activities such as enhancing the organism immune and anti-tumor function, and have few toxic and side effects. So the polysaccharides show a wide application prospect in the prevention and therapy of tumor. The tumor microenvironment consists of tumor cells and tumor cells' surrounding environment. The tumor microenvironment not only plays a key role in the development of tumor, but also is a potential treasure for searching new ways to treat tumor. In this review, we summarized polysaccharides' regulation effects on tumor microenvironment progression and tried to give a new theoretical basis for the exploitation of polysaccharides with anti-tumor activity.

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http://dx.doi.org/10.1080/10408398.2015.1077191DOI Listing

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