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Dynamic flow synthesis of porous organic cages. | LitMetric

Dynamic flow synthesis of porous organic cages.

Chem Commun (Camb)

Department of Chemistry and Centre for Materials Discovery, University of Liverpool, Crown Street, Liverpool, L69 7ZD, UK.

Published: December 2015

AI Article Synopsis

  • The synthesis of two imine-based porous organic cages was done continuously instead of in separate batches.* -
  • The same flow reactor was used to mix the building blocks of the cages in different ratios, creating mixtures.* -
  • A purification process (HPLC) was applied to one mixture, enabling quick production of a desymmetrised cage molecule.*

Article Abstract

The dynamic covalent synthesis of two imine-based porous organic cages was successfully transferred from batch to continuous flow. The same flow reactor was then used to scramble the constituents of these two cages in differing ratios to form cage mixtures. Preparative HPLC purification of one of these mixtures allowed rapid access to a desymmetrised cage molecule.

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Source
http://dx.doi.org/10.1039/c5cc07447aDOI Listing

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