Episodic memory shows striking improvement during early childhood. However, neural contributions to these behavioral changes are not well understood. This study examined associations between episodic memory and volume of subregions (head, body, and tail) of the hippocampus-a structure known to support episodic memory in school-aged children and adults-during early childhood (n = 45). Results revealed significant positive relations between episodic memory and volume of the hippocampal head in both the left and right hemispheres for 6- but not 4-year-old children, suggesting brain-behavior relations vary across development. These findings add new information regarding neural mechanisms of change in memory development during early childhood and suggest that developmental differences in hippocampal subregions may contribute to age-related differences in episodic memory ability.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875696PMC
http://dx.doi.org/10.1111/cdev.12445DOI Listing

Publication Analysis

Top Keywords

episodic memory
24
early childhood
16
developmental differences
8
relations episodic
8
memory volume
8
memory
7
episodic
6
differences relations
4
memory hippocampal
4
hippocampal subregion
4

Similar Publications

Background And Objectives: Lipid metabolism in older adults is affected by various factors including biological aging, functional decline, reduced physiologic reserve, and nutrient intake. The dysregulation of lipid metabolism could adversely affect brain health. This study investigated the association between year-to-year intraindividual lipid variability and subsequent risk of cognitive decline and dementia in community-dwelling older adults.

View Article and Find Full Text PDF

Pattern separation and pattern completion in the hippocampus play a critical role in episodic learning and memory. However, there is limited empirical evidence supporting the role of the hippocampal circuit in these processes during complex continuous experiences. In this study, we analyzed high-resolution fMRI data from the "Forrest Gump" open-access dataset (16 participants) using a sliding-window temporal autocorrelation approach to investigate whether the canonical hippocampal circuit (DG-CA3-CA1-SUB) shows evidence consistent with the occurrence of pattern separation or pattern completion during a naturalistic audio movie task.

View Article and Find Full Text PDF

Background: Although impaired cognitive control is common during the acute detoxification phase of substance use disorders (SUD) and is considered a major cause of relapse, it remains unclear after prolonged methadone maintenance treatment (MMT). The aim of the present study was to elucidate cognitive control in individuals with heroin use disorder (HUD) after prolonged MMT and its association with previous relapse.

Methods: A total of 63 HUD subjects (41 subjects with previous relapse and 22 non-relapse subjects, mean MMT duration: 12.

View Article and Find Full Text PDF

Network segregation during episodic memory shows age-invariant relations with memory performance from 7 to 82 years.

Neurobiol Aging

January 2025

Center for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo 0317, Norway; Department of Radiology and Nuclear Medicine, University of Oslo, Oslo 0317, Norway.

Lower episodic memory capability, as seen in development and aging compared with younger adulthood, may partly depend on lower brain network segregation. Here, our objective was twofold: (1) test this hypothesis using within- and between-network functional connectivity (FC) during episodic memory encoding and retrieval, in two independent samples (n = 734, age 7-82 years). (2) Assess associations with age and the ability to predict memory comparing task-general FC and memory-modulated FC.

View Article and Find Full Text PDF

Background: Superagers, older adults with exceptional cognitive abilities, show preserved brain structure compared to typical older adults. We investigated whether superagers have biologically younger brains based on their structural integrity.

Methods: A cohort of 153 older adults (aged 61-93) was recruited, with 63 classified as superagers based on superior episodic memory and 90 as typical older adults, of whom 64 were followed up after two years.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!