AI Article Synopsis
- The SCCS (Scientific Committee on Consumer Safety) has determined that Polyaminopropyl Biguanide (PHMB) is unsafe for consumers in cosmetic spray formulations and all cosmetic products at concentrations up to 0.3%.
- To ensure safety, PHMB may need to be used at lower concentrations or with restrictions on specific types of cosmetic products.
- Additional studies on how PHMB is absorbed through the skin in various cosmetic formulations are necessary, along with general exposure data from non-cosmetic uses to fully assess its safety.
Article Abstract
Conclusion of the opinion: On the basis of the data available, the SCCS concludes that Polyaminopropyl Biguanide (PHMB) is not safe for consumers when used as a preservative in cosmetic spray formulations and in all cosmetic products up to the maximum concentration of 0.3%. The safe use could be based on a lower use concentration and/or restrictions with regard to cosmetic products' categories. Dermal absorption studies on additional representative cosmetic formulations are needed. PHMB is used in a variety of applications other than cosmetics. General exposure data from sources others than cosmetics should be submitted for the assessment of the aggregate exposure of PHMB.
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| http://dx.doi.org/10.1016/j.yrtph.2015.09.035 | DOI Listing |
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