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Trends in certifications of overall vision impairment and that due to diabetic retinopathy/maculopathy in England and Wales, 2009/2010 to 2019/2020: a retrospective database analysis.
BMJ Open
January 2025
Diabetes Research Group, Swansea University, Swansea, UK.
Objectives: This study aims to report the trends in the certification of both sight impairment (SI) and severe sight impairment (SSI) in England and Wales during the period of 2010 to 2020, prior to the COVID-19 pandemic. The focus is on diabetic retinopathy/maculopathy as the key causative factor.
Design: Retrospective database analysis.
The effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Randomised Study.
Intensive Care Med Exp
January 2025
Department of Life Sciences, Aberystwyth University, Ceredigion, UK.
Purpose: The landiolol and organ failure in patients with septic shock (STRESS-L study) included a pre-planned sub-study to assess the effect of landiolol treatment on inflammatory and metabolomic markers.
Methods: Samples collected from 91 patients randomised to STRESS-L were profiled for immune and metabolomic markers. A panel of pro- and anti-inflammatory cytokines were measured through commercially acquired multiplex Luminex assays and statistically analysed by individual and cluster-level analysis (patient).
Evaluating Use of Empagliflozin for Diabetes Management in Veterans With Chronic Kidney Disease.
Fed Pract
November 2024
Hershel "Woody" Williams Veterans Affairs Medical Center, Huntington, West Virginia.
Background: About 1 in 4 veterans have diabetes, and many also have chronic kidney disease (CKD). Empagliflozin, a sodium-glucose cotransporter-2 (SGLT-2) inhibitor, is approved for the treatment of diabetes. The purpose of this study was to evaluate the effectiveness of empagliflozin on hemoglobin A (HbA) in patients with CKD.
View Article and Find Full Text PDFRepresentation Quotients to Examine Diversity in Ophthalmology Residency Applicants and Matriculants.
JAMA Ophthalmol
January 2025
Division of Ophthalmology, Warren Alpert Medical School of Brown University, Providence, Rhode Island.
Importance: A diverse ophthalmic workforce is key to equitable care, and identifying areas of underrepresentation is important in tackling vision care disparities.
Objective: To evaluate the diversity of applicants and matriculants in ophthalmology residency programs relative to medical school graduates and analyze the intersection of race and gender within this pathway.
Design, Setting, And Participants: This retrospective cross-sectional study conducted from 2022 to 2024 used representation quotients (RQs) using reports from the Association of University Professors of Ophthalmology and San Francisco Match, along with demographic data from the Association of American Medical Colleges from 2008 to 2021.
Drivers of forest productivity in two regions of the United States: Relative impacts of management and environmental variables.
J Environ Manage
January 2025
Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, 35487, USA. Electronic address:
Climate, environmental conditions, and management strategies are key factors affecting forest net ecosystem production (NEP). However, little is known about the relationship between management approaches and regional to continental-scale forest productivity. In this study, we utilized forests of the U.
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