The authors described a radioimmunoassay developed for the determination of beta 2-microglobulin (beta 2-M) concentration in human serum and urine using 125I-labeled beta 2-M. This method permitted the determination of beta 2-M concentration within 0.5-50 mg/l in the blood serum and within 0.02-50 mg/l in urine. beta 2-M concentration determined by this assay, was 1.71 +/- 0.58 mg/l in the blood serum and 0.097 +/- 0.32 mg/l in the urine of healthy persons.
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