Since we first reported the antitumor efficacy of IL-27 in 2004, accumulating evidence obtained by several groups using a variety of preclinical mouse models indicates that IL-27 possesses potent antitumor activity against various types of tumors through multiple mechanisms depending on the characteristics of individual tumors without apparent adverse effects.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589049 | PMC |
| http://dx.doi.org/10.1080/2162402X.2015.1042200 | DOI Listing |
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