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Preparation and optimization of niosome encapsulated meropenem for significant antibacterial and anti-biofilm activity against methicillin-resistant isolates.
Heliyon
August 2024
Department of Biology, Roudehen Branch, Islamic Azad University, Roudehen, Iran.
Background: One of the targeted drug delivery systems is the use of nanocarriers, and one of these drug delivery systems is niosome. Niosome have a nano-vesicular structure and are composed of non-ionic surfactants. Objective: In this study, various niosome-encapsulated meropenem formulations were prepared.
View Article and Find Full Text PDFPreparation of graft copolymer of chitosan-poly ortho-toluidine for antibacterial properties.
Heliyon
July 2024
Department of Chemistry, Nika Pooyesh Industrial Research Institute, Tehran, Iran.
Article Synopsis
- The study focuses on creating a copolymer, Cs--POT, by grafting poly ortho-toluidine onto chitosan to enhance its properties, including improved electrical conductivity and biocompatibility.
- Characterization techniques like FTIR, UV-visible, and H NMR spectroscopy, along with thermal analyses (TGA and DSC), confirm the successful grafting and properties of the copolymer.
- Cs--POT exhibits antibacterial effects against various bacteria, showing potential applications in tissue and bone repair, as well as in delivering anti-cancer drugs.
Enhanced third-order nonlinear optical properties of ZnO@C-N composite microspheres.
Spectrochim Acta A Mol Biomol Spectrosc
December 2024
Department of Physics, Faculty of Science, Shahid Rajaee Teacher Training University, Lavizan, P. O. Box 16788-15811, Tehran, Iran. Electronic address:
We report the third-order nonlinear optical (NLO) properties of ZnO@C-N composite microspheres and pure ZnO which have been investigated with the Z-scan technique under continuous wave laser. ZnO@C-N composite microspheres have been hydrothermally synthesized at two different precursor concentrations to have structures at different impurity levels. Moreover, pure ZnO is prepared under the annealing process.
View Article and Find Full Text PDFHigh-Intensity Interval Training Ameliorates Tramadol-Induced Nephrotoxicity and Oxidative Stress in Experimental Rats.
Cureus
June 2024
Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, IRN.
Introduction: Tramadol (TRA) is an opioid analgesic widely prescribed for moderate-to-severe pain; however, its abuse and chronic use have been associated with kidney damage. Considering the protective role of exercise training in reducing organ damage, this study aimed to assess the influence of high-intensity interval training (HIIT) on a male rat's kidney following chronic TRA administration.
Methods: In this experimental study, 30 male Wistar rats were assigned to the following groups: control (CON; animals received normal saline five days a week in the first month and three days a week in the second month), exercise (EXE; animals conducted HIIT training according to exercise protocol five days a week for two months), TRA (animals received TRA 50 mg/kg (i.
Exploring the power of data mining for uncovering traditional medicinal plant knowledge: A case study in Shahrbabak, Iran.
PLoS One
June 2024
Faculty of Agriculture, Department of Horticultural Science, University of Jiroft, Jiroft, Iran.
The present study recorded indigenous knowledge of medicinal plants in Shahrbabak, Iran. We described a method using data mining algorithms to predict medicinal plants' mode of application. Twenty-oneindividuals aged 28 to 81 were interviewed.
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