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Genetic profiling of extended-spectrum β-Lactamase and carbapenemase-producing Escherichia coli O157:H7 from clinical samples among diarrheal patients in Shashemene, Ethiopia.
BMC Infect Dis
January 2025
Department of Microbiology, Immunology and Parasitology, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Background: Escherichia coli (E. coli) O157:H7, associated with diarrhea, poses a global health risk. In Ethiopia, where diarrhea is common, there is limited knowledge about these resistant strains and a lack of data on Extended-Spectrum β-Lactamase (ESBL) and carbapenemase production.
View Article and Find Full Text PDFText Messaging Versus Postal Reminders to Improve Participation in a Colorectal Cancer Screening Program: Randomized Controlled Trial.
JMIR Mhealth Uhealth
January 2025
see Acknowledgments, .
Article Synopsis
- The study evaluated SMS text reminders for colorectal cancer screening in Catalonia, finding that they were less effective than standard postal reminders in increasing participation rates.
- The trial involved over 24,000 participants aged 50 to 69 and was halted early due to lower than expected participation in the SMS group (17.2% vs. 21.9% for control).
- Despite initial low participation, a recovery strategy of sending additional postal reminders to nonparticipants in the SMS group improved overall participation rates to 29.3%.
Microbiome testing in Europe: navigating analytical, ethical and regulatory challenges.
Microbiome
December 2024
Pharmabiotic Research Institute, 11100, Narbonne, France.
Background: In recent years, human microbiome research has flourished and has drawn attention from both healthcare professionals and general consumers as the human microbiome is now recognized as having a significant influence on human health. This has led to the emergence of companies offering microbiome testing services. Some of these services are sold directly to the consumer via companies' websites or via medical laboratory websites.
View Article and Find Full Text PDFGut microbiota and mesenteric adipose tissue interactions in shaping phenotypes and treatment strategies for Crohn's disease.
World J Gastroenterol
December 2024
Department of General Surgery, Guglielmo da Saliceto Hospital, Piacenza 29100, Italy.
In this letter, we commented on the article by Wu . We examined the interactions between mesenteric adipose tissue, creeping fat, and gut microbiota in Crohn's disease (CD), a condition marked by chronic gastrointestinal inflammation with a rising global incidence. The pathogenesis of CD involves complex genetic, environmental, and microbial factors.
View Article and Find Full Text PDFArticle Synopsis
- Entamoeba histolytica is a parasite causing intestinal amebiasis, particularly prevalent in tropical areas and a major health issue in developing countries. Traditional diagnostic methods can cause delays in treatment, exacerbating patient conditions.
- A case involving a 59-year-old HIV-positive man revealed how initial testing misdiagnosed his illness, but advanced diagnostics using the FilmArray GI Panel quickly identified E. histolytica in under an hour.
- The successful and prompt treatment with antiamoebic drugs significantly improved the patient's health, highlighting the importance of rapid diagnosis in managing gastrointestinal infections effectively.
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