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Introduction: Understanding differences in clinical outcomes between PBSCT and BMT is important, and this study compared outcomes of HLA-matched related PBSCT and BMT using reduced-intensity conditioning (RIC) in adult acute myeloid leukemia (AML) patients.
Methods: Data from 402 patients who underwent either PBSCT ( = 294) or BMT ( = 108) between 2000 and 2022 were analyzed using the Japanese nationwide registry database. The primary endpoint was overall survival (OS), and secondary endpoints included disease-free survival (DFS), non-relapse mortality (NRM), and GVHD.
Continuous atrial fibrillation monitoring using a wearable smartwatch: Using long-term Holter as reference.
Digit Health
January 2025
Department of Cardiology, Peking University First Hospital, Beijing, China.
Background: Wearables satisfactorily detect atrial fibrillation (AF) longer than 1 hour. Our study aims to evaluate smartwatch performances for long-term AF monitoring, including AF with short durations.
Methods: This prospective study enrolled AF patients from 2020 to 2023.
Predicting Extended Intensive Care Unit Stay Following Coronary Artery Bypass Grafting and Its Impact on Hospitalization and Mortality.
J Clin Med Res
January 2025
Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Background: Coronary artery bypass grafting (CABG) is a prevalent surgical procedure aimed at alleviating symptoms and improving survival in patients with coronary artery disease (CAD). Postoperative care typically necessitates an intensive care unit (ICU) stay, which is ideally less than 24 h. However, various preoperative, intraoperative, and postoperative factors can prolong ICU stays, adversely affecting hospital resources, patient outcomes, and overall healthcare costs.
View Article and Find Full Text PDFEffect of hyperhomocysteinemia on the prognostic value of triglyceride glucose index in patients with acute coronary syndrome.
Front Cardiovasc Med
January 2025
Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Department of Cardiology, Beijing Anzhen Hospital, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing, China.
Background: The prognostic value of triglyceride-glucose (TyG) has been well described in patients with coronary artery disease (CAD). Hyperhomocysteinemia (HHcy) promotes insulin resistance and has also been regarded as a potential risk factor for cardiovascular disease. However, the prognostic value of TyG in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) and the interaction between TyG and HHcy remain unclear.
View Article and Find Full Text PDFReagent efficiency and analytical sensitivity optimization for a reliable SARS-CoV-2 pool-based testing strategy.
Heliyon
January 2025
Bupa Lab, part of Bupa, La Florida, Santiago, Chile.
Background: The SARS-CoV-2 pandemic caused millions of infections worldwide. Among the strategies for effective containment, frequent and massive testing was fundamental. Although sample pooling allows multiplying the installed analysis capacity, the definition of the number of samples to include in a pool is commonly guided more by economic parameters than analytical quality.
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