BRAF Inhibitor-Induced Panniculitis: Appearance on 18F-FDG PET/CT.

Clin Nucl Med

From the Department of Radiology, Mayo Clinic, Rochester, MN.

Published: March 2016

BRAF inhibitors vemurafenib and dabrafenib have become the standard of care for treatment of stage IV metastatic melanoma harboring a BRAF mutation. Panniculitis is a rare but known adverse side effect of these agents and presents with tender erythematous nodules. These nodules may demonstrate uptake on F-FDG PET/CT, which may mimic metastatic disease in patients undergoing treatment. We present a case of BRAF inhibitor-induced panniculitis in a patient with stage IV metastatic melanoma and discuss the imaging findings on F-FDG PET/CT.

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Source
http://dx.doi.org/10.1097/RLU.0000000000001027DOI Listing

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