Sleep benefits the consolidation of psychological memory, and there are hints that sleep likewise supports immunological memory formation. Comparing psychological and immunological domains, we make the case for active system consolidation that is similarly established in both domains and partly conveyed by the same sleep-associated processes. In the psychological domain, neuronal reactivation of declarative memory during slow-wave sleep (SWS) promotes the redistribution of representations initially stored in hippocampal circuitry to extra-hippocampal circuitry for long-term storage. In the immunological domain, SWS seems to favor the redistribution of antigenic memories initially held by antigen-presenting cells, to persisting T cells serving as a long-term store. Because storage capacities are limited in both systems, system consolidation presumably reduces information by abstracting 'gist' for long-term storage.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.tins.2015.07.007 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Supervised Toothbrushing Programmes: Understanding Barriers and Facilitators to Implementation.
Community Dent Oral Epidemiol
January 2025
School of Clinical Dentistry, University of Sheffield, Sheffield, UK.
Objectives: Supervised toothbrushing programmes (STPs), whereby children brush their teeth at nursery or school with a fluoride toothpaste under staff supervision, are a clinically and cost-effective intervention to reduce dental caries. However, uptake is varied, and the reasons unknown. The aim was to use an implementation science approach to explore the perspectives of key stakeholders on the barriers and facilitators at each level of implementation of STPs.
View Article and Find Full Text PDFThe signification of the principle of constancy in Freud's psychoanalysis.
Int J Psychoanal
December 2024
Independent Researcher.
This article examines the signification of the principle of constancy in Freud's pre-psychoanalytic drafts and papers and in . It is argued that Freud's principle differs from seemingly similar principles proposed by Breuer and Fechner, and that it constitutes an assumption about the maintaining of a constant amount of mobile biophysical energy whose purpose is to return to equilibrium, but, proceeding from the primary functions of discharge (principle of inertia) and accumulation (exigencies of life), to consolidate an asymmetry within the nervous system. This gives rise to a set of quasi-psychological dualisms: an energetic dualism between kinetic and tonic energy; a systemic dualism between impermeable and permeable neurons; and a processual dualism between courses of the excitation with and without the inhibiting influence of the ego.
View Article and Find Full Text PDFUnderstanding patient safety during earthquakes: a phenomenological study of disaster response.
BMJ Qual Saf
January 2025
Medical Services and Techniques, Health Services Vocational School, Marmara Üniversitesi, Istanbul, Turkey.
Background: Natural hazards, such as earthquakes, pose a significant risk to both the public and healthcare professionals, jeopardising patient safety due to the disruption of healthcare systems and services. This study aimed to explore the lived experiences of healthcare professionals concerning patient safety during natural hazards, specifically earthquakes.
Methods: Employing a descriptive phenomenological approach, the study followed the Consolidated Criteria for Reporting Qualitative Research guidelines.
Topography of putative bi-directional interaction between hippocampal sharp-wave ripples and neocortical slow oscillations.
Neuron
January 2025
Neuroscience Institute, Langone Medical Center, New York University, New York, NY, USA; Department of Physiology and Neuroscience, Langone Medical Center, New York University, New York, NY, USA; Department of Neurology, Langone Medical Center, New York University, New York, NY, USA. Electronic address:
Systems consolidation relies on coordination between hippocampal sharp-wave ripples (SWRs) and neocortical UP/DOWN states during sleep. However, whether this coupling exists across the neocortex and the mechanisms enabling it remains unknown. By combining electrophysiology in mouse hippocampus (HPC) and retrosplenial cortex (RSC) with wide-field imaging of the dorsal neocortex, we found spatially and temporally precise bi-directional hippocampo-neocortical interaction.
View Article and Find Full Text PDFScreening, identification, and application of anaerobic ammonia oxidizing bacteria in activated sludge systems: A comprehensive review.
J Environ Manage
January 2025
School of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang, China. Electronic address:
Anaerobic ammonium oxidation (Anammox) has garnered significant attention due to its ability to eliminate the need for aeration and supplementary carbon sources in biological nitrogen removal process, relying on the capacity of anaerobic ammonium oxidizing bacteria (AnAOB) to directly convert ammonium and nitrite nitrogen into nitrogen gas. This review consolidates the latest advancements in AnAOB research, outlining the mechanisms and enzymatic processes of Anammox, and summarizing the molecular biological techniques used for studying AnAOB, such as 16s rRNA sequencing, qPCR, and metagenomic sequencing. Additionally, it also overviews the currently identified AnAOB species and their distinct metabolic traits, while consolidating strategies to improve their performance.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!