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Integration of (B)-containing elements through large chromosome fragment exchange in . | LitMetric

Integration of (B)-containing elements through large chromosome fragment exchange in .

Mob Genet Elements

Department of Infectious, Parasitic and Immune-Mediated Diseases; Istituto Superiore di Sanità ; Rome, Italy.

Published: February 2015

AI Article Synopsis

  • * This study focused on the genomes of recipient strains that obtained Tn or Tn-like elements, confirming that the integration of these elements into their genomes involved homologous recombination.
  • * The findings indicated that transposons did not transfer to a strain when DNAse was present, implying a transformation-like process might have facilitated the acquisition of these elements in the recipient.

Article Abstract

In , (B) genes are located on mobile elements like Tn and Tn. In previous studies, some of these elements were transferred by conjugation-like mechanisms, mobilized by helper conjugative systems. In this study, we analyzed the genomes of several recipient strains that acquired either Tn or Tn-like elements. We demonstrated that the integration of the transposons in the genome of the recipient cell was always due to homologous recombination events, involving exchange of large chromosomal segments. We did not observed transposon transfer to a strain in presence of DNAse, suggesting that a possible transformation-like mechanism occurred in this recipient.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590004PMC
http://dx.doi.org/10.1080/2159256X.2015.1006111DOI Listing

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