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Article Synopsis
  • - A 72-year-old man with faintness was diagnosed with sick sinus syndrome and experienced an Adams-Stokes attack, leading to the implantation of a permanent pacemaker.
  • - After developing seizures, CT scans revealed herpes simplex virus DNA in the cerebrospinal fluid, prompting immediate treatment with intravenous acyclovir.
  • - Despite treatment, the patient's condition worsened with additional brain damage and ultimately led to death from aspiration pneumonia, highlighting the need to consider herpes encephalitis in cases of sinus node dysfunction.
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Sintilimab-Induced Myocarditis in a Patient with Gastric Cancer: A Case Report and Literature Review.

J Cardiovasc Dev Dis

October 2023

Department of Cardiology, Zhongnan Hospital, Wuhan University, No. 169 Donghu Road, Wuchang District, Wuhan 430071, China.

Immune checkpoint inhibitors (ICIs) have emerged as a powerful and efficacious therapeutic approach for many cancer patients. Sintilimab is a fully human IgG4 monoclonal antibody that binds with programmed cell death receptor-1 (PD-1) to block its interaction with ligands, thereby enhancing the antitumor effects of T cells. However, ICIs may induce immune-related adverse events (irAEs) in various systems and organs, with fulminant myocarditis being the most severe one.

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Perioperative coronary artery spasm after off-pump coronary artery bypass grafting in the non-manipulated coronary artery.

BMC Cardiovasc Disord

April 2022

Department of Cardiac Surgery, Chest Hospital, Tianjin University, No. 261 Taierzhuang South Road, Jinnan District, Tianjin, 300222, China.

Background: Perioperative coronary artery spasm (CAS) following coronary artery bypass grafting (CABG) is a severe or lethal condition that is rarely reported. In addition, rare cases with CAS following CABG in the non-manipulated coronary artery are angiographically documented in the perioperative period. We aimed to report our experiences on the diagnosis and treatment of a case with CAS following off-pump CABG in the non-manipulated coronary artery.

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Background: At present, temporary pacemaker implantation is very common in the treatment of cardiovascular diseases in adults. However, the number of pediatric pacemakers implanted is still relatively small, and relevant research is also far less than that of adults. This study aimed to explore the application of temporary pacemakers in children with acute and critical cardiovascular diseases.

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Case Report: Hypothyroidism Misdiagnosed as Fulminant Myocarditis in a Child.

Front Cardiovasc Med

June 2021

Department of Pediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu, China.

Hypothyroidism can lead to bradycardia, reduced cardiac output, cardiac enlargement, and abnormal electrocardiogram. However, hemodynamic instability and malignant arrhythmias due to hypothyroidism is rarely reported in children. We report the case of a child with third-degree atrioventricular block, cardiogenic shock, and Adams Stokes Syndrome, who was initially misdiagnosed with fulminant myocarditis and was later found to have hypothyroidism during treatment.

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