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Between Scylla and Charybdis: Navigating heart failure management in complex older adults.
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Department of Medicine, Division of Cardiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
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Between Scylla and Charybdis: Fixed-ratio avoidance response effort and unavoidable shock extinction in humans.
Behav Brain Res
February 2025
School of Psychology, Swansea University, Singleton Campus, Swansea SA2 8PP, United Kingdom.
Avoidance of potential threat may become maladaptive when it is indiscriminate and resistant to change. Here, we investigated the resistance to change of high and low avoidance response effort when avoidance extinction involved unavoidable presentations of the aversive event (shock) in humans. Following fear conditioning, participants prevented upcoming shock delivery by responding on high (i.
View Article and Find Full Text PDFBetween Scylla and Charybdis?-Health insurance claims-data to monitor quality of service delivery in ophthalmology.
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December 2024
Eye Clinic, Lucerne Cantonal Hospital LUKS, Lucerne 16, Switzerland.
The seminal work of Wennberg and Gittelsohn in 1973 emphasised the importance of health information for informed decision-making. This led to the creation of the Dartmouth Health Atlas in 1996, which has become an important resource for monitoring health services in the USA. The Dartmouth Health Atlas research revealed the existence of variation in health care without benefit to patients, and the dependence of health care use on local resource supply.
View Article and Find Full Text PDFBetween Scylla and Charybdis: assessing the multidimensional aspects of pain behaviors in rats using a double avoidance place preference paradigm.
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August 2024
University of Strasbourg, Centre National de la Recherche Scientifique, Cognitive and Adaptive Neuroscience Laboratory, Strasbourg, France.
Although the behavioral response to pain is complex and involves supraspinal processes, assessment of pain symptoms in animal models still mainly relies on reflex-based nociceptive tests, which do not account for the affective-motivational nor cognitive components of pain. We introduce a double avoidance place preference paradigm, an integrated testing procedure in freely moving rats that relies on the conflict between the avoidance of a dark compartment in which a thermal ramp is activated, and the escape towards an aversive brightly lit compartment. We were able to differentiate the first nociceptive threshold from the temperature of definitive escape from the dark compartment, conveying information on the adaptive behavior of animals.
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