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[Myasthenia as the cause of vertical diplopia in the elderly].
Ophthalmologie
July 2024
Klinik und Poliklinik für Neurologie, Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Myasthenia gravis is a well-understood autoimmune disease of the neuromuscular synapse that is medicinally treatable with favorable results and therefore should not be overlooked in the differential diagnostic evaluation of vertical diplopia. Myasthenia is primarily a clinical diagnosis. Positive indications include double vision of fluctuating severity, diurnal variations, double vision after lengthy gaze fixation on a distant object and in the primary position as well as diplopia in various visual directions, often associated with a varying extent of ptosis.
View Article and Find Full Text PDFUnusual Presentation of Double-seronegative Myasthenia Gravis with Positive Anti-LRP4 Antibody: Diagnostic Utility of a Videofluoroscopic Swallowing Study.
Intern Med
January 2025
Department of Neurology, JA Toride Medical Center, Japan.
An 86-year-old woman was admitted to our hospital with cryptogenic progressive dyspnea and dysphagia following a tracheostomy procedure 4 months prior to presentation. She exhibited fluctuating diplopia, bilateral vocal fold paralysis, normal nerve test results, negative findings for serum anti-acetylcholine receptor and anti-muscle-specific kinase antibodies, and positive findings for anti-LDL receptor-related protein 4 (LRP4). A videofluoroscopic swallowing study (VFSS) with edrophonium revealed an improvement in bulbar paralysis.
View Article and Find Full Text PDFOcular Myasthenia Gravis As Unilateral Ptosis and External Ophthalmoplegia: A Case Report.
Cureus
March 2024
Pediatrics, Khyber Medical College/Khyber Teaching Hospital, Peshawar, PAK.
Myasthenia gravis (MG) is an autoimmune disorder characterized by fluctuating weakness and fatigue in ocular, bulbar, limb, or respiratory muscles. Initially, more than half of MG patients experience isolated ocular symptoms, such as ptosis, diplopia, or muscle paresis. This case report presents a unique occurrence of MG in a four-year-old female, showcasing a two-year history of sudden onset, persistent yet fluctuating unilateral ptosis accompanied by exo-deviation and adduction deficit in the right eye.
View Article and Find Full Text PDFDiplopia in Movement Disorders: A Systematic Review of the Literature.
J Pers Med
February 2024
Department of Neurology, County Clinic Hospital, 500365 Brașov, Romania.
Introduction: Although the reported frequency of diplopia is between 10 to 40% of patients with Parkinson's disease (PD) and other movement disorders, it remains one of the most undiagnosed non-motor symptoms. Furthermore, it has a major impact on the quality of life of these patients. The aim of this study is to systematically review the literature regarding the frequency, causes, and implications of diplopia in movement disorders.
View Article and Find Full Text PDFIsolated pseudo‑abducens palsy and contralateral occipital headache with thalamic stroke: A case report and mini‑review of the literature.
Med Int (Lond)
February 2024
Department of Medicine, Federal University of Santa Maria, Santa Maria, RS 97105-900, Brazil.
The abducens nerve (sixth cranial nerve) is essential for lateral eye movement, and its malfunction can cause a variety of issues with vision. Pseudo-abducens palsy is a rare neurological condition that causes a limitation in eye abduction, while the abducens nerve is still functioning. Thalamic pain syndrome, a severe complication of cerebrovascular events, presents as intense neuropathic pain provoked by temperature fluctuations.
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