We consider a multistage cancer model in which cells are arranged in a -dimensional integer lattice. Starting with all wild-type cells, we prove results about the distribution of the first time when two neutral mutations have accumulated in some cell in dimensions ≥ 2, extending work done by Komarova [12] for = 1.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587779 | PMC |
| http://dx.doi.org/10.1214/13-AAP989 | DOI Listing |
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