AI Article Synopsis

  • Anomalous aortic origin of the coronary artery (AAOCA) with an interarterial course is a rare congenital heart condition, and surgical methods for treatment have changed over the years as we've managed 259 adult patients since 1974.
  • Our study analyzed the outcomes of 31 patients who underwent various surgical interventions, with most being unroofing procedures and a mean follow-up of nearly 4 years showing good results.
  • The findings indicate that only a small number of patients with AAOCA need surgery, and our multidisciplinary approach ensures excellent anatomical and functional outcomes post-surgery.

Article Abstract

Background: Anomalous aortic origin of the coronary artery (AAOCA) with an interarterial (IAC) course is an uncommon congenital anomaly. Surgical indications and repair techniques have evolved. We have managed 259 adult patients with AAOCA over 40 years. Our management strategy includes anatomic- and function-based surveillance to select surgical candidates. We reviewed our surgical cohort and analyzed anatomic and functional outcomes.

Methods: We queried our heart center databases to obtain the names of all patients with AAOCA managed at our institution between 1974 and 2014. We performed a retrospective chart review.

Results: Two hundred fifty-nine patients were managed for AAOCA. Sixty-one underwent surgical intervention. Twenty-six with associated coronary atherosclerosis were excluded. Thirty-one who underwent surgical repair were analyzed. Mean age was 42.5 ± 2.7 years. Twenty-four patients (77.4%) had right AAOCA. Six (19.4%) had left AAOCA. One (3.2%) had bilateral coronary anomalies. Repair techniques included 21 unroofing procedures (67.7%), 6 translocations (19.4%), and 4 coronary artery bypass grafting (CABG) procedures (12.9%). Mean follow-up was 3.8 ± 0.8 years. Thirteen patients underwent follow-up anatomic testing with computed tomography. Twelve of these patients had widely patent coronary arteries, and 1 patient had mild coronary artery stenosis. Seventeen patients underwent functional testing. Fifteen of these patients had no evidence of ischemia. One patient had reversible ischemia after CABG, and 1 had subclinical ischemia after unroofing. There was 1 late mortality from endocarditis.

Conclusions: Our multidisciplinary program uses a treatment algorithm to select patients with AAOCA for surgical intervention. Only a small subset requires an operation, and we favor unroofing and translocation techniques. With this paradigm, outcomes are excellent, as validated with anatomic- and function-based testing.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.athoracsur.2015.07.003DOI Listing

Publication Analysis

Top Keywords

coronary artery
16
anatomic- function-based
12
patients aaoca
12
patients
9
anomalous aortic
8
aortic origin
8
origin coronary
8
surgical repair
8
repair techniques
8
underwent surgical
8

Similar Publications

Cardiac Positron Emission Tomography (PET) can be used for the assessment of myocardial perfusion. Compared to other cardiac imaging techniques, notably Single Photon Emission Computer Tomography (SPECT), cardiac PET offers superior image resolution, higher accuracy, quantitative measures of myocardial perfusion, lower radiation exposure, and shorter image acquisition time. However, PET tends to be costlier and less widely available than SPECT due to the specialized equipment needed for generating the necessary radiotracers.

View Article and Find Full Text PDF

Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide, necessitating advancements in diagnostic techniques. Coronary CT angiography (CCTA) has emerged as a pivotal non-invasive tool for evaluating coronary artery anatomy and detecting atherosclerotic plaque burden with high spatial resolution. This review explores the evolution of CCTA, highlighting its technological advancements, clinical applications, and challenges.

View Article and Find Full Text PDF

Which Test is Best for Pain in the Chest?

R I Med J (2013)

February 2025

Professor of Medicine, Clinician Educator, Warren Alpert Medical School, Brown University; Associate Chief, Cardiology, Brown University Health Cardiovascular Institute, Providence, Rhode Island.

Chest pain is one of the most common chief complaints seen in both the emergency department (ED) and primary care settings.1,2 It is estimated that 20-40% of the general population will suffer from chest pain at some point throughout their lives.3 Interestingly although obstructive coronary artery disease (CAD) prevalence has declined, chest pain as a presenting symptom has become increasingly common over the last decade.

View Article and Find Full Text PDF

Update in Cardiovascular Prevention: From Risk Scores to Imaging.

R I Med J (2013)

February 2025

Division of Cardiology, Department of Medicine, Brown University, Providence RI.

Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of morbidity and mortality worldwide. This review explores the evolving evidence base surrounding ASCVD prevention, particularly regarding nontraditional biomarkers, risk scores, and cardiovascular imaging modalities. Additionally, this review examines cardiovascular risk scores, including the PREVENT and MESA-CHD scores, which incorporate both traditional and nontraditional factors, thereby aspiring to offer a more equitable and precise risk assessment.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!