In China, the crude drug licorice ("kanzo" in Japanese, "gancao" in Chinese) has been used both dried and roasted as the situation demands from ancient times. The meaning of "roasted licorice" is simply roasted and honey-roasted in ancient and modern times, respectively. However, it is not clear medicinal purposes of processed licorice or why licorice processed with honey began to be used. We researched ancient literature and found that the main objective of roasting was to change the property of licorice from cool to warm (i.e., dried licorice had the effect of draining fire), while roasted licorice was used as an energy supplement, having a digestive effect and thus warming the body. Meanwhile, doctors began using honey-roasted licorice to treat throat pain from the Song dynasty, and then at the end of the Qing dynasty, honey-roasted licorice was expected to have the same effects of roasted licorice (i.e., supplementing energy and having a digestive effect).
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J Ethnopharmacol
July 2024
School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address:
BMC Complement Med Ther
November 2023
Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Alkhartoom square, Egypt, Alexandria, 21521, Egypt.
Background: Roasting, honey-roasting and fermentation are the most common pre-processing procedures of licorice roots. They were shown to noticeably change the composition of extracts. In this work, the common alterations in licorice secondary metabolites by processing were interpreted.
View Article and Find Full Text PDFJ Ethnopharmacol
November 2023
School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address:
Ethnopharmacological Relevance: Honey-processed licorice (HPL) is the roasted product of licorice. It is recorded in the "Shang Han Lun" that licorice has better protection on heart after honey-processed. However, researches regarding its protective effect on the heart and the distribution of HPL in vivo are still limited.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
December 2022
School of Pharmacy, Nanjing University of Chinese Medicine Nanjing 210023, China.
To explore the color value changes after processing and further explore the correlations between color values and internal components, we established a rapid evaluation method for the quality of Glycyrrhizae Radix et Rhizoma and Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle. In this study, the color values of Glycyrrhizae Radix et Rhizoma and Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle were digitized by a spectrophotometer, and the standard ranges of color values of the two herbal medicines were established. Further, a discriminant analysis model was established to quickly and accurately distinguish the two herbal medicines.
View Article and Find Full Text PDFMolecules
November 2022
The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250033, China.
Licorice (Gan-Cao, licorice) is a natural antioxidant and roasted licorice is the most common processing specification used in traditional Chinese medicine prescriptions. Traditional Chinese medicine theory deems that the honey-roasting process can promote the efficacy of licorice, including tonifying the spleen and augmenting "Qi" (energy). The antioxidant activity and mechanisms underlying roasted licorice have not yet been reported.
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