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Differential Association of Salivary Proinflammatory Mediators with Type 2 Diabetes: A Network Meta-Analysis.
Iran J Public Health
December 2024
Medical Department, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China.
Background: Salivary compounds can be used as diagnostic markers for changes in the oral cavity that cause oral problems in type 2 diabetes mellitus (T2DM).
Methods: This meta-analysis searched PubMed/Medline, EMBASE, Scopus and Cochrane Library, and the Web of Science until Nov 2023. The observational studies included patients with T2DM and healthy controls aged > 18 yr with no oral health problems or systematic or periodontal diseases.
Associations between maternal per- and polyfluoroalkyl substances exposure and lipid levels in maternal and cord blood: The Japan environment and Children's study.
Environ Res
December 2024
Department of Preventive Medicine and Public Health, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan; Center for Perinatal, Pediatric, and Environmental Epidemiology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan; Department of Occupational Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.
Despite numerous studies, the associations between per- and polyfluoroalkyl substances (PFAS) exposure and various lipid levels in pregnant women remain ambiguous, especially concerning the association with cord blood lipids. This analysis included 20,960 pregnant women enrolled in the Japan Environment and Children's Study, recruited between 2011 and 2014. Non-fasting plasma samples collected before 22 weeks of gestation were examined for PFAS concentrations.
View Article and Find Full Text PDFVitamin D, periodontitis and tooth loss in older Irish adults.
Br J Nutr
September 2024
Dublin Dental University Hospital, Trinity College Dublin, DublinD02 F859, Republic of Ireland.
The aim of this study is to investigate whether 25-hydroxyvitamin D (25(OH)D) is associated with periodontitis and tooth loss in older adults. A total of 2346 adults underwent a detailed dental examination as part of the health assessment of a national population study - The Irish Longitudinal Study of Ageing. 25(OH)D analysis was performed on frozen non-fasting total plasma using LC-MS.
View Article and Find Full Text PDFLipid and glucose profiles in pregnant women with HIV on tenofovir-based antiretroviral therapy.
Clin Infect Dis
September 2024
Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA USA.
Objective: Tenofovir alafenamide (TAF)-based antiretroviral therapy (ART) regimens have been associated with adverse changes in lipid and glucose profiles compared with tenofovir disoproxil fumarate (TDF)-based ART, but data in pregnancy is limited. We evaluated metabolic markers in pregnant women with HIV after starting TAF- vs TDF-based ART.
Methods: We analyzed data within the IMPAACT 2010/VESTED trial, which demonstrated better pregnancy outcomes in pregnant women randomized to initiate TAF/Emtricitabine/Dolutegravir (TAF/FTC+DTG; n=217) or TDF/FTC+DTG (n=215).
Contributing factors to hypophosphatemia development in critically Ill ventilated patients: a retrospective cohort study.
Sci Rep
August 2024
Department of General Intensive Care, Rabin Medical Centre, Beilinson Hospital, Petah Tikva, Israel.
Article Synopsis
- Hypophosphatemia is a significant concern in critically ill patients receiving nutritional support, with over 59% of studied patients developing the condition.
- Factors such as age, BMI, pre-existing diabetes, and certain admission conditions were linked to a lower risk of developing hypophosphatemia, while trauma increased the risk.
- Interestingly, hypophosphatemia was found to be associated with a decreased risk of mortality, though factors like age and specific health scores remained critical indicators of ICU mortality.
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