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Case Report: Prenatal ultrasound presentation of congenital melanocytic nevus syndrome.
Front Pediatr
December 2024
Department of Ultrasound, Jinan Maternity and Child Care Hospital, Jinan, Shandong, China.
Congenital melanocytic nevus (CMN) syndrome is a rare, non-familial neural ectodermal dysplasia characterized by CMN combined with extracutaneous abnormalities, predominantly involving the central nervous system (CNS). The pathogenesis of CMN syndrome is thought to result from early post-zygotic somatic mutations. CNS melanosis frequently affects the anterior temporal lobes, brainstem, cerebellum, and cerebral cortex.
View Article and Find Full Text PDFCongenital goiter in an alpaca (Vicugna pacos) fetus concomitant with brain pathology in the dam: composing the puzzle.
Vet Res Commun
January 2025
Department of Veterinary Medicine, University of Perugia, Via San Costanzo, 4, Perugia, 06126, Italy.
This study describes the congenital goiter in an alpaca (Vicugna pacos) fetus aborted in November 2021 with the clinical and pathological findings in the dam that was found dead on the farm three weeks after a miscarriage. The dam was a black coat alpaca bred in the Netherlands, imported in Italy in January 2021, and housed in a farm of central Italy for breeding purposes. Signalment and clinical data on dam and fetus were collected from the farmer and referring veterinarian.
View Article and Find Full Text PDFSpinal anesthesia for cesarean delivery in a laboring patient with known cranial arachnoid cyst: a case report.
Int J Obstet Anesth
December 2024
Department of Anesthesiology, Perioperative and Pain Medicine, Brigham & Women's Hospital, Harvard Medical School, United States.
Article Synopsis
- Arachnoid cysts are generally fluid-filled and asymptomatic, requiring no surgery; however, their safety during neuraxial procedures in pregnant patients is not well-documented.
- The case presented involves the anesthetic management of a pregnant patient with a significant arachnoid cyst affecting the cerebellum who was in labor.
- Following a multidisciplinary approach, neuraxial labor anesthesia was deemed suitable, and the patient ultimately received spinal anesthesia for a cesarean delivery due to fetal distress.
Impact of high maternal body mass index on fetal cerebral cortical and cerebellar volumes.
J Perinat Med
January 2025
Tufts Medical Center, Mother Infant Research Institute, Boston, MA, USA.
Objectives: Maternal obesity increases a child's risk of neurodevelopmental impairment. However, little is known about the impact of maternal obesity on fetal brain development.
Methods: We prospectively recruited 20 healthy pregnant women across the range of pre-pregnancy or first-trimester body mass index (BMI) and performed fetal brain magnetic resonance imaging (MRI) of their healthy singleton fetuses.
T* relaxometry of fetal brain structures using low-field (0.55T) MRI.
Magn Reson Med
December 2024
Research Department of Early Life Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Purpose: Human brain development during gestation is complex, as both structure and function are rapidly forming. Structural imaging methods using MRI are well developed to explore these changes, but functional imaging tools are lacking. Low-field MRI is a promising modality to bridge this gap.
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