Characterization of Five Zoonotic Streptococcus suis Strains from Germany, Including One Isolate from a Recent Fatal Case of Streptococcal Toxic Shock-Like Syndrome in a Hunter.

J Clin Microbiol

Institute for Microbiology, University of Veterinary Medicine Hannover, Hannover, Germany Institute for Bacteriology and Mycology, Centre of Infectious Diseases, College of Veterinary Medicine, University Leipzig, Leipzig, Germany

Published: December 2015

A Streptococcus suis isolate from a German hunter with streptococcal toxic shock-like syndrome (STSLS) and four additional zoonotic isolates were genotyped as mrp(+) epf* (variant 1890) sly(+) cps2(+). All five zoonotic German strains were characterized by high multiplication in human blood samples ex vivo, but induction of only low levels of proinflammatory cytokines compared to a Chinese STSLS strain.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652130PMC
http://dx.doi.org/10.1128/JCM.02578-15DOI Listing

Publication Analysis

Top Keywords

streptococcus suis
8
streptococcal toxic
8
toxic shock-like
8
shock-like syndrome
8
characterization zoonotic
4
zoonotic streptococcus
4
suis strains
4
strains germany
4
germany including
4
including isolate
4

Similar Publications

Oreochromicin-2 shows antimicrobial and immunostimulant effect against respiratory pathogens in pigs.

Res Vet Sci

December 2024

Metabolic Modifiers for Aquaculture, Agricultural Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), 31st Avenue and 190, Havana 10600, Cuba. Electronic address:

Article Synopsis
  • Porcine respiratory diseases significantly affect pig production, with common pathogens like Streptococcus suis and Pasteurella multocida also posing risks to human health.
  • The overuse of traditional antibiotics has led to antimicrobial resistance, highlighting the need for alternative treatments such as antimicrobial peptides (AMPs).
  • Oreochromicin-2 (Oreoch-2), an AMP from fish, showed promising results in reducing bacterial loads and improving health in pigs, making it a potential candidate for treating respiratory diseases in swine.
View Article and Find Full Text PDF

Streptococcus suis (S. suis) is a major pathogen for pigs, causing large economic losses to the swine industry. Moreover, this bacterium has a zoonotic potential, being capable of infecting humans in close contact with pigs or, less frequently, through contact with pork products.

View Article and Find Full Text PDF

Background: Streptococcus suis (S. suis) is a major swine pathogen and a significant zoonotic agent, causing substantial economic losses in the swine sector and having considerable public health importance. The control and management of S.

View Article and Find Full Text PDF

Effects of environment regulating T4SS on virulence and adaptability of Streptococcus suis.

Environ Res

January 2025

College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China; Henan Engineering Research Center of Livestock and Poultry Emerging Disease Detection and Control, Luoyang, China. Electronic address:

Streptococcus suis (S. suis) represents a significant bacterial pathogen, with its zoonotic transmission from infected or deceased pigs to humans posing a serious threat to public health. The type IV secretion system (T4SS), a critical virulence factor of S.

View Article and Find Full Text PDF

A universal live vaccine platform against multiple serotypes Streptococcus suis based on polyvalent antigen protein.

Vaccine

January 2025

College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, Jiangsu, China; Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China; Joint International Research Laboratory of Agriculture and Agri-Product Safety, Yangzhou University (JIRLAAPS), Yangzhou, China. Electronic address:

Streptococcus suis (S. suis) is a major pathogen that poses a long-term threat to swine populations. Due to its foodborne transmission, this pathogen has recently emerged as a leading cause of meningitis in humans, presenting a significant public health challenge.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!