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Genomic characteristics and molecular epidemiology of MRSA from medical centers in Mexico: Results from the Invifar network.
PLoS One
January 2025
Departamento de Bioquímica y Medicina Molecular, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
Introduction: The methicillin-resistant Staphylococcus aureus (MRSA) genome varies by geographical location. This study aims to determine the genomic characteristics of MRSA using whole-genome sequencing (WGS) data from medical centers in Mexico and to explore the associations between antimicrobial resistance genes and virulence factors.
Methods: This study included 27 clinical isolates collected from sterile sites at eight centers in Mexico in 2022 and 2023.
Can febrile neutropenia re-invent its self?
Curr Opin Oncol
January 2025
Service de Médecine Oncologique, Université Libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (HUB), Institut Jules Bordet, Bruxelles, Belgique.
Purpose Of Review: Febrile neutropenia as a complication of cytotoxic chemotherapies, remains a major event in the medical journey of hematology and oncology patients. In this review, we are trying to review the new elements and highlights that are shaping febrile neutropenia in nowadays.
Recent Findings: Introduction of risk-stratification, expanded use of granulocyte-colony stimulating factor and oral treatment for selected patients and rapid administration of antibiotics revolutionized the treatment of febrile neutropenia.
Emergence of Extended spectrum β-lactamase (ESBL) and carbapenemase producing in mid-stream urine cultures of patients presenting in outpatient department of tertiary care hospital with uncomplicated cystitis (2016-2022): A retrospective analysis of Laboratory data.
Pak J Med Sci
January 2025
Ikram Din Ujjan, PhD Department of Pathology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Objective: To determine the prevalence of antimicrobial resistance (AMR) in isolated from urine cultures of patients with uncomplicated cystitis in Pakistan. Another objective was to analyze and compare the resistance rates of to specific antibiotics, conducting a year-by-year evaluation of these rates to identify trends and changes over the past seven years.
Methods: Retrospective analysis of susceptibility data of isolated from midstream urine culture samples of patients presenting in outpatient department with uncomplicated cystitis, from January 2016 to December 2022 in the section of Microbiology, Liaquat University of Medical and Health Sciences was done.
Antimicrobial Resistance Patterns of Clinically Isolated Strains of Acinetobacter baumannii in a Tertiary Care Hospital in Libya.
Cureus
December 2024
Department of Genetic Engineering, Libyan Biotechnology Research Center, Tripoli, LBY.
Objective: accounts for a notable percentage of hospital-acquired infections. The widespread resistance to multiple antibiotic classes complicates treatment efforts. This study aims to find out the pattern of susceptibility of multidrug-resistant (MDRAB) isolated from clinical specimens to antibiotics recommended for testing and use for and to determine a local guide at Tripoli University Hospital (TUH), Tripoli, Libya for the empirical antibiotic treatment of MDRAB based on the susceptibility pattern identified.
View Article and Find Full Text PDFA systematic review of recent outbreaks and the efficacy and safety of drugs approved for the treatment of infections.
IJID Reg
March 2025
Department of Pharmacy Practice, School of Pharmacy, IMU University, Kuala Lumpur, Malaysia.
A systematic review was conducted to critically analyze the outbreaks, efficacy, and safety of drugs used to treat various infections. Four drugs-azithromycin, ceftriaxone, ciprofloxacin, and amoxicillin-are commonly used to treat infections, and all four drugs were included in this review. This review found that, of these, azithromycin and ceftriaxone were more effective in treating infections based on the patient's length of stay in the hospital and the rate at which the fever was resolved.
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