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Unveiling Sociocultural Barriers to Breast Cancer Awareness Among the South Asian Population: Case Study of Bangladesh and West Bengal, India.
JMIR Hum Factors
January 2025
New College of Florida, Sarasota, FL, United States.
Background: Bangladesh and West Bengal, India, are 2 densely populated South Asian neighboring regions with many socioeconomic and cultural similarities. In dealing with breast cancer (BC)-related issues, statistics show that people from these regions are having similar problems and fates. According to the Global Cancer Statistics 2020 and 2012 reports, for BC (particularly female BC), the age-standardized incidence rate is approximately 22 to 25 per 100,000 people, and the age-standardized mortality rate is approximately 11 to 13 per 100,000 for these areas.
View Article and Find Full Text PDFBeyond Homochirality: Computer Modeling Hints of Heterochiral Proteins in Early and Extraterrestrial Life.
Astrobiology
December 2024
Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Bari, Italy.
Agent-based simulations are set to describe the early biotic selection of oligomers made of monomers of different chirality. The simulations consider the spatial distribution of agents and resources, the balance of biomass of different chirality, and the balance of chemical energy. Following the well-known Wald's hypothesis, a disadvantage is attributed to the change in chirality along the biochemical sequence.
View Article and Find Full Text PDFMicroRNA-mediated Ets1 repression in retinal endothelial cells: A novel anti-angiogenic mechanism in nonproliferative diabetic retinopathy.
Diabetes Obes Metab
January 2025
Department of Genetics, College of Basic Medical Sciences, Jilin University, Changchun, China.
Aims: This study aimed to discover the regulatory mechanisms contributing to angiogenesis in nonproliferative diabetic retinopathy (NPDR).
Materials And Methods: This study employed a case-control design involving type 2 diabetes patients with and without NPDR. We utilised microRNA sequencing to analyse plasma and retina samples from T2D patients, to identify both existing and novel microRNAs relevant to retinal health.
Sector-Wide Approach (SWAp) in Healthcare-A Mixed-Methods Assessment of Health SWAps in Nepal and Bangladesh.
Int J Environ Res Public Health
December 2024
Department of Business Administration and Health Care Management, University of Greifswald, 17489 Greifswald, Germany.
Background: The sector-wide approach (SWAp) is an instrument of cooperation between external development partners (EDPs) and the government of a country. Its main purpose is the coordination, alignment and harmonisation of activities between EDPs and between EDPs and the respective government by covering the entire sector with one major programme.
Methods: The main objective of this paper is to analyse the performance of the SWAps in two countries and draw conclusions about the appropriateness of SWAps as financing instruments in the healthcare sector under certain conditions.
Toward optimal disease surveillance with graph-based active learning.
Proc Natl Acad Sci U S A
December 2024
Department of Biology, University of Oxford, Oxford OX1 3SZ, United Kingdom.
Article Synopsis
- Tracking emerging pathogens is essential for effective public health responses, and this study models resource allocation for testing as a decision-making problem involving locations as nodes on a graph.
- The researchers evaluate different active learning policies for selecting testing locations, comparing their effectiveness in various outbreak scenarios through simulations on both synthetic and real-world networks.
- A new policy that considers the distance-weighted average entropy shows improved performance over existing methods, emphasizing the importance of balancing exploration and exploitation in developing surveillance strategies for pathogen monitoring.
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