Background: Because the prevalence and characteristics of primary headache have yet to be thoroughly studied in patients with hypersomnia disorders, including narcolepsy and idiopathic hypersomnia, we examined these parameters in the Japanese population.
Methods: In a multicentre cross-sectional survey, among 576 consecutive outpatients with sleep disorders, 68 narcolepsy patients and 35 idiopathic hypersomnia patients were included. Additionally, 61 healthy control subjects participated. Semi-structured headache questionnaires were administered to all participants.
Results: The patients with narcolepsy (52.9%) and idiopathic hypersomnia (77.1%) more frequently experienced headache than the healthy controls (24.6%; p<0.0001). The prevalence rates were 23.5%, 41.2% and 4.9% for migraine (p<0.0001) and 16.2%, 23.5% and 14.8% (p = 0.58) for tension-type headache among the narcolepsy patients, the idiopathic hypersomnia patients and the control subjects, respectively. Those who experienced migraine more frequently experienced excessive daytime sleepiness, defined as an Epworth Sleepiness Scale score of ≥10, than those who did not experience headache among the patients with narcolepsy (93.8% vs. 65.6%, p = 0.040) and idiopathic hypersomnia (86.7% vs. 37.5%, p = 0.026). Dream-enacting behaviour (DEB), as evaluated by the rapid eye movement sleep disorders questionnaire, was more frequently observed in the narcolepsy patients than in the idiopathic hypersomnia patients and the control subjects. An increased DEB frequency was observed in the narcolepsy patients with migraines compared to those without headache.
Conclusions: Migraines were frequently observed in patients with narcolepsy and idiopathic hypersomnia. DEB is a characteristic of narcolepsy patients. Further studies are required to assess the factors that contribute to migraines in narcolepsy and idiopathic hypersomnia patients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587931 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139229 | PLOS |
Publication Analysis
Top Keywords
Similar Publications
Families of adults with idiopathic hypersomnia and narcolepsy: psychosocial impact and contribution to symptom management.
J Clin Sleep Med
December 2024
Patient advocate.
Study Objectives: This study examined the impact of central disorders of hypersomnolence (CDH) on family members of adult patients, the ways family members assist with managing CDH, and family members' utilization and satisfaction with information and support.
Methods: Participants were adults (N=100) with an adult family member diagnosed with idiopathic hypersomnia or narcolepsy. They completed a survey which included the Family Reported Outcome Measure (FROM-16), checklists, satisfaction ratings, and open-response questions.
Variability of excessive daytime sleepiness and cataplexy according to seasonality: A study in central disorders of hypersomnolence.
J Sleep Res
January 2025
Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Seasonality of excessive daytime sleepiness has been proposed, yet no research has specifically investigated its impact on daytime sleepiness and cataplexy in central disorders of hypersomnolence. This study examined seasonal variations in daytime sleepiness and cataplexy in narcolepsy type 1, narcolepsy type 2 and idiopathic hypersomnia. Patients included in the study were on stable pharmacological treatment, and participated in sleep medicine interviews to assess diurnal sleepiness and daytime napping and completed the Epworth Sleepiness Scale to assess excessive daytime sleepiness (Epworth Sleepiness Scale ≥ 10).
View Article and Find Full Text PDFThe impact of idiopathic hypersomnia on the social lives of young adults.
Sleep Health
December 2024
Boston Children's Hospital, Boston, Massachusetts, United States; Harvard Medical School, Boston, Massachusetts, United States; Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States; Dana-Farber Cancer Institute, Boston, Massachusetts, United States.
Objectives: People with idiopathic hypersomnia report significant impairment in their lives due to idiopathic hypersomnia symptoms, and this likely includes an impact on social relationship health. This study investigated the effects of idiopathic hypersomnia on social relationships (friends, romantic, and sexual) during the key developmental period of young adulthood.
Methods: Young adults (N = 106; 18-39years) with idiopathic hypersomnia were recruited through national hypersomnia patient organizations.
Excellent response to levetiracetam for recurrent prolonged sleep attacks in an 18-year-old male: a case report.
J Med Case Rep
December 2024
Ibn Sina Hospital, Kuwait, Kuwait.
Background: Sleep disorders are a common health problem that can be classified into many types that are distinguished by their history and characteristics. In this case report, we discuss a case of a patient suffering from recurrent unusual prolonged sleep attacks lasting up to 9 days that responded excellently to levetiracetam.
Case Presentation: An 18-year-old Syrian male patient presented to the neurology department complaining of recurrent prolonged sleep episodes lasting for 9 days.
Advances in sleep research in 2024.
Lancet Neurol
January 2025
National Reference Centre for Orphan Diseases, Narcolepsy, Idiopathic Hypersomnia, and Kleine-Levin Syndrome, Sleep-Wake Disorders Unit, Department of Neurology, Gui-de-Chauliac Hospital, CHU Montpellier, University of Montpellier, 34000 Montpellier, France; Institute of Neurosciences of Montpellier, INSERM, Montpellier, France. Electronic address:
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!