[Study on Chemical Constituents of Lonicera japonica Bud].

Objective: To study the chemical constituents of Lonicera japonica bud.

Methods: The compounds were isolated and repeatedly purified by silica gel column chromatography, gel column chromatography and ODS chromatography. The structures were elucidated by physicochemical properties, MS and NMR.

Results: Eight compounds were isolated and their structures were identified as protocatechuic acid (1), 5-hydroxy-7,3',4'-trimethoxyflavone (2), hyperoside (3), 4-hydroxycinnamic acid (4), ethyl caffeate(5), apigenin (6), 5-hydroxy-6,7,8,4'-tetramethoxyflavone (7), and ethyl laurate (8).

Conclusion: Compounds 5, 7 and 8 are obtained from this genus for the first time.