Effects of waterborne fluoxetine on stress response and osmoregulation in zebrafish.

Environ Toxicol Pharmacol

Universidade Federal de Santa Maria (UFSM), Programa de Pós-Graduação em Farmacologia, Campus Universitário, Camobi, Santa Maria, RS, Brazil; Universidade de Passo Fundo (UPF), Programa de Pós-Graduação em Bioexperimentação, Campus I, Bairro São José, Caixa Postal 611, Passo Fundo, RS, Brazil. Electronic address:

Published: November 2015

The presence of fluoxetine in aquatic environments has been reported for decades. Here, we investigate the effects of exposure to fluoxetine on the stress response and osmoregulation in zebrafish. We show that stress response alters osmoregulation and that fluoxetine inhibits these stress-related changes in osmoregulation. The results suggest that the presence of fluoxetine in aquatic ecosystems can cause changes in response to stress and osmoregulation in fish.

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Source
http://dx.doi.org/10.1016/j.etap.2015.09.001DOI Listing

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